在宫颈参数正常的妇女中,胚胎减少为双胞胎(ERTT)与三胞胎环扎:一项回顾性研究

A. Dawood, A. Soliman, Sherif Elshwaikh, A. Elkhyat
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引用次数: 0

摘要

目的:比较ERTT治疗三胞胎妊娠结扎的疗效和安全性。材料与方法:对266例患者的资料进行回顾性分析。采用ERTT治疗的符合条件的患者(n=120)分为研究组,采用环切术治疗的患者(n=121)分为对照组。第10周前用卵母细胞抽吸针进行胚胎缩小。14-16周时进行结扎。对两组的产科和新生儿不良结局进行评估。结果:环切术(对照组)120例,ERTT(研究组)121例。两组患者流产率(p值=0.002)、分娩时间(p值=0.0001)、分娩时胎龄(p值=0.0001)、分娩方式(p值=0.0002)差异均有统计学意义。两组胎儿出生体重(P值=0.0002)、新生儿总并发症(P值= 0.009)和新生儿重症监护病房需求(P值= 0.0003)差异有统计学意义。结论:与保守的环扎术相比,胚胎减少到双胞胎(ERTT)手术改善了三胞胎妊娠的产科和新生儿结局。
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Embryo Reduction to Twins (ERTT) Versus Cerclage in Triplets in Women with Normal Cervical Parameters: A Retrospective Study
Objective: To compare the efficacy and safety of ERTT to cerclage in triplet pregnancy. Material and Methods: In this retrospective study, files of 266 patients were examined. Eligible patients managed by ERTT (n=120) were allocated into study group while patients managed by cerclage (n=121) were allocated into control group. Embryo reduction was done by oocyte aspiration needle before 10 th week. Cerclage was done at 14-16 weeks. Obstetrical and neonatal adverse outcomes were assessed in both groups. Results: One hundred and twenty cases were allocated in cerclage (control) group, 121 cases were allocated in ERTT (study) group. There was significant difference between both groups regarding abortion rate ( P-value =0.002), delivery time ( P-value =0.0001), gestational age at time of delivery (P-value=0.0001) and mode of delivery ( P-value =0.0002). There was significant difference between both groups regarding fetal birth weight ( P-value =0.0002), overall neonatal complications ( P value 0.009) and need of NICU ( P=value 0.0003). Conclusion: Embryo reduction to twins (ERTT) procedures improved obstetrical and neonatal outcomes in triplet pregnancies compared to conservative management with cerclage procedure.
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