科索沃共和国杜卡金地区的肥胖和男性不育症

Afrim Zeqiraj, Zafer Gashi, Sadi Bexheti, S. Elezaj, S. Berisha, A. Shabani
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引用次数: 1

摘要

本文将研究导致男性超重的原因,内分泌腺激素分泌紊乱,以及肥胖对不育症的影响。这项工作的目的,是通过超重男性来确定男性不育的程度。这项工作是在科索沃共和国的佩贾地区进行的。材料和方法:样本于2015年3月至2017年3月在科索沃共和国佩贾的Biolab-Zafi内分泌实验室进行。结果显示,BMI为29.97±3.22的男性不育率明显高于BMI为23.52±2.0的男性(p<0.00001)。我们还发现,与对照组的FSH(4.72±2.63)相比,工作组的FSH(7.99±8.21)显著增加(p<0.008)。我们还发现,与对照组LH(3.79±1.99)相比,工作组LH(5.06±2.74)明显增加(p<0.002)。我们还发现,与对照组的泌乳素13.05±4.8相比,工作组的泌乳素17.37±7.66明显增加(p<0.00004)。我们还发现,与对照组睾酮5.79±1.48相比,睾酮组(4.16±1.88)的工作组发生率显著增加(p<0.005)。结论:本研究结果表明,在我国科索沃共和国,肥胖是公共卫生发展中日益严重的问题,是男性不育症出现的重要危险因素。BMI增长的影响往往会增加射精中DNA损伤的风险,增加激素水平(FSH, LH,催乳素,睾酮),降低精子参数(数量减少,运动减少),氧化应激,高血压,心脏病,糖尿病和其他慢性疾病的风险。
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Obesity and Male Infertility in The Dukagjin Region in Republic of Kosovo
In this paper will be studied the causes that can cause overweight in men, and the disorder of hormone production from endocrine glands, as well as the influence of obesity in infertility. Purpose of the work, it is to determine the degree of male infertility by overweight men. The work was done in the region of Peja, in the Republic of Kosovo. Materials and methods, the sampling was done in March 2015-March 2017 in the Biolab-Zafi endocrinology laboratory in Peja, Republic of Kosovo. Our results show a significant increase in male infertility rates with BMI 29.97 ± 3.22, compared with men with BMI 23.52 ± 2.0 (p<0.00001). We also found a significant increase in working group rates with FSH 7.99 ± 8.21, compared to control group FSH 4.72 ± 2.63 (p<0.008). We also found a significant increase in working group rates with LH 5.06 ± 2.74, compared to control group LH 3.79 ± 1.99 (p<0.002). We also found a significant increase in working group rates with Prolactin 17.37 ± 7.66, compared to control group Prolacitn 13.05 ± 4.8 (p<0.00004). We also found a significant increase in working group rates with Testosterone 4.16 ± 1.88, compared to control group Testosterone 5.79 ± 1.48 (p<0.005). Conclusion, the results from this study show that obesity in our country, the Republic of Kosovo, is a growing problem in the development of public health, and is an important risk factor for the appearance of male infertility. The effects of BMI growth tend to increase the risk of DNA damage in ejaculates, increase in hormone levels (FSH, LH, prolactin, testosterone), decrease sperm parameters (decrease in number, decrease in movement), oxidative stress, Risk of hypertension, cardiac disorders, diabetes and other chronic disorders.
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