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引用次数: 2
摘要
[27]中华医学杂志2019;41(3): 327-32•DOI: 10.14744/etd.2019.22230原创文章-开放获取本作品采用知识共享署名-非商业4.0国际许可协议。Halil İbrahim Erdoğdu, Fatih Kara血液透析患者的残留肾功能及相关因素目的:残留肾功能(RKF)是终末期肾病(ESRD)患者肾脏剩余容量的重要标志。RKF在血液透析(HD)第一年下降的事实最近引起了更多的关注。本研究的目的是确定和分析接受HD治疗的患者当前RKF水平及相关因素。材料和方法:研究在卡尔斯州立医院进行,共73例HD患者。测定残余肾尿素清除率(KRU)以测定RKF。患者的尿量在一周的第一次HD治疗结束和下一次HD治疗开始之间测定。按KRU水平分为3组:2 mL/min。比较两组间HD治疗时间、生物统计学特征、生化和激素分析、HD充分性、ESRD病因和合并症。p值小于0.05被认为具有统计学意义(置信区间为95%)。结果:KRU值与HD治疗时间(p<0.001)、ESRD病因(p=0.037)、血钾水平(p=0.028)、磷水平(p=0.036)、尿量(p<0.001)、超滤(UF)量(p=0.002)、体重指数(p=0.002)差异均有统计学意义。尿量<100 mL/d的患者HD治疗持续时间较长,为6.9±4.2年(p=0.021),用用量较大(723±230 mL/h) (p<0.001)。结论:本研究的发现可能有助于对HD治疗的月度解释和调节,而不是提供RKF丧失的因果关系的解释。需要更多的研究,包括在一定时间间隔测量RKF和长期观察。
期刊介绍:
Erciyes Medical Journal (Erciyes Med J) is the international, peer-reviewed, open access publication of Erciyes University School of Medicine. The journal, which has been in continuous publication since 1978, is a publication published on March, June, September, and December. The publication language of the journal is English. The journal accepts clinical and experimental research articles in different fields of medicine, original case reports, letters to the editor and invited reviews for publication. Research articles and case reports on regionally frequent and specific medical topics are prioritized. Manuscripts on national and international scientific meetings and symposiums and manuscripts sharing scientific correspondence and scientific knowledge between authors and their readers are also published.