使用vat -光聚合增材制造工艺制备的医用级牙种植体力学性能的实验表征

IF 1 Q4 ENGINEERING, MANUFACTURING Journal of Micro and Nano-Manufacturing Pub Date : 2022-06-27 DOI:10.1115/msec2022-85436
Regan Raines, James B. Day, Roozbeh Salary
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引用次数: 1

摘要

本研究的首要目标是制造机械坚固且尺寸准确的牙种植体,用于治疗牙骨折、畸形和结构畸形,重点是口腔颌面外科应用。为了实现这一目标,本研究的目的是研究几种三周期最小表面(TPMS)支架的机械性能,这些支架由医用级光聚合物树脂组成,采用数字光处理(DLP)工艺制造。DLP是一种光聚合增材制造工艺;它已经成为一种高分辨率的方法,用于制造广泛的生物组织和组织工程应用结构。然而,DLP过程本质上是复杂的;该工艺的复杂性源于复杂的物理化学现象(如紫外光光聚合)以及树脂(光聚合物)与工艺的相互作用,这些相互作用可能对制备的牙科支架的机械性能、表面形态以及最终的功能特性产生不利影响。因此,基于物理的工艺和材料表征将是不可避免的需要。在这项研究中,几个TPMS支架(具有复杂的内部几何形状)被制造,基于医用级光聚合物树脂。用压缩试验机对制备的牙支架的压缩性能进行了测试。此外,在模拟体液(SBF)中评估了支架的生物活性。这项研究的结果为制造具有可调医学和功能特性的复杂牙种植体铺平了道路。
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Experimental Characterization of the Mechanical Properties of Medical-Grade Dental Implants, Fabricated Using Vat-Photopolymerization Additive Manufacturing Process
The overarching goal of this research work is to fabricate mechanically-robust and dimensionally-accurate dental implants for the treatment of dental fractures, anomalies, and structural deformities with a focus on oral and maxillofacial surgery applications. In pursuit of this goal, the objective of the work is to investigate the mechanical properties of several triply periodic minimal surface (TPMS) scaffolds, composed of a medical-grade photopolymer resin, fabricated using digital light processing (DLP) process. DLP is a vat-photopolymerization additive manufacturing process; it has emerged as a high-resolution method for the fabrication of a broad spectrum of biological tissues and constructs for tissue engineering applications. However, the DLP process is intrinsically complex; the complexity of the process stems from complex physiochemical phenomena (such as UV light photopolymerization) as well as resin (photopolymer)-process interactions, which may adversely influence the mechanical properties, the surface morphology, and ultimately the functional characteristics of fabricated dental scaffolds. Consequently, physics-based process and material characterization would be an inevitable need. In this study, several TPMS scaffolds (having complex internal geometries) were fabricated, based on a medical-grade photopolymer resin. The compression properties of the fabricated dental scaffolds were measured using a compression testing machine. In addition, the bioactivity of the scaffolds was assessed in a simulated body fluid (SBF). The outcomes of this study pave the way for the fabrication of complex dental implants with tunable medical and functional properties.
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来源期刊
Journal of Micro and Nano-Manufacturing
Journal of Micro and Nano-Manufacturing ENGINEERING, MANUFACTURING-
CiteScore
2.70
自引率
0.00%
发文量
12
期刊介绍: The Journal of Micro and Nano-Manufacturing provides a forum for the rapid dissemination of original theoretical and applied research in the areas of micro- and nano-manufacturing that are related to process innovation, accuracy, and precision, throughput enhancement, material utilization, compact equipment development, environmental and life-cycle analysis, and predictive modeling of manufacturing processes with feature sizes less than one hundred micrometers. Papers addressing special needs in emerging areas, such as biomedical devices, drug manufacturing, water and energy, are also encouraged. Areas of interest including, but not limited to: Unit micro- and nano-manufacturing processes; Hybrid manufacturing processes combining bottom-up and top-down processes; Hybrid manufacturing processes utilizing various energy sources (optical, mechanical, electrical, solar, etc.) to achieve multi-scale features and resolution; High-throughput micro- and nano-manufacturing processes; Equipment development; Predictive modeling and simulation of materials and/or systems enabling point-of-need or scaled-up micro- and nano-manufacturing; Metrology at the micro- and nano-scales over large areas; Sensors and sensor integration; Design algorithms for multi-scale manufacturing; Life cycle analysis; Logistics and material handling related to micro- and nano-manufacturing.
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