Impact of zinc on thyroid metabolism

Submit Manuscript | http://medcraveonline.com is essential for normal functioning of metabolic homeostasis, immune system, cell stimulation, enzyme activity, protection against oxidative stress, and neural transmission.4,5 It works as co-enzyme factor for many enzymes which are involved in various metabolic processes and it is essential for sensitizing the tissues to thyroid hormone.6 Zinc is also involved in cell differentiation, proliferation, cell repairing and renewal. The importance of zinc in endocrine system is that it effect on growth, endocrine homeostasis, and thyroid function and on glucose metabolism.7 Deficiency of zinc in the body may result in decreased levels of secretion of thyroid hormones which affects the normal metabolism of the body and resting metabolic rate. Some of the studies shown that deficiency of zinc is associated with enhanced the expression of hepatic thyroxine-5’-monodeiodinase enzyme activity which catalyses the thyroid hormone inactivation.8,9