尼日利亚西北部药物滥用模式:城市社区的实验室调查

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Nigerian Journal of Basic and Clinical Sciences Pub Date : 2022-01-01 DOI:10.4103/njbcs.njbcs_43_21
Sanni Musa, Zainab F Ibrahim, I. Isah, K. Abdulsalam
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引用次数: 2

摘要

背景:现有资料表明,药物滥用在全世界构成了重大的政治、社会和健康挑战。药物的可获得性、消极的同伴压力、贫穷和挫折都是增加药物滥用负担的因素。尿液药物检测(UDT)是分析滥用物质的一种可靠的实验室方法,因为许多药物及其代谢物在尿液中可以检测到较长时间。目的:发现尼日利亚西北部青少年药物滥用的实验室模式,并根据总体模式提出建议,以减少对社会的影响。背景和设计:对到临床实验室进行尿检的患者的二次资料进行回顾性横断面调查。方法和材料:经过培训的人员在监督下采集新鲜尿液样本,使用定性免疫分析技术进行分析。一种药物的存在是通过达到该药物的检测极限来确定的。使用统计分析:使用社会科学统计软件包(SPSS)第2版软件对数据进行分析。结果:药物滥用筛查率为60.9%。在检测呈阳性的人中,97%为男性,3%为女性。大多数参与者是30岁以下的年轻人。观察到的模式显示,少数参与者(26.48%)的尿液中只存在一种药物,而73.53%的参与者在尿液样本中检测出两到五种药物的多种物质呈阳性。结论:该地区药物滥用发生率高,且多数为多种药物使用者。
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Pattern of substance abuse in Northwestern Nigeria: A laboratory survey in an urban community
Context: Available information indicates that substance abuse poses a major political, social, and health challenge worldwide. Availability of drugs, negative peer pressure, poverty, and frustration are among the factors that increase the burden of substance abuse. Urine drug testing (UDT) is a reliable laboratory method of analyzing substances of abuse because many drugs and their metabolites remain detectable in the urine for longer periods. Aims: To detect the laboratory pattern of substance abuse among youths in North-Western Nigeria and to make recommendations based on the overall pattern to curtail the effect on society. Settings and Design: A retrospective cross-sectional survey of secondary data of patients who presented to a clinical laboratory for urine drug tests. Methods and Material: Trained personnel carried out a supervised collection of fresh urine samples, which were analyzed using a qualitative immunoassay technique. The presence of a drug was determined by reaching the drug's limit of detection. Statistical Analysis Used: Data were analyzed using a Statistical Package for the Social Science (SPSS) version 2 software. Results: The screen prevalence of substance abuse was 60.9%. Among those who tested positive, 97% were males, whereas 3% were females. The majority of participants were youths below 30 years of age. The observed pattern revealed a few of the participants (26.48%) had only one drug substance present in their urine, whereas 73.53% tested positive for multiple substances ranging from two to five drugs in a urine sample. Conclusion: A high prevalence of substance abuse was observed and most of the participants were multidrug users.
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来源期刊
Nigerian Journal of Basic and Clinical Sciences
Nigerian Journal of Basic and Clinical Sciences MEDICINE, GENERAL & INTERNAL-
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0.20
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0.00%
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8
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