利用前撕囊瓣作为角膜保护罩保护白内障手术中的角膜内皮

Stjepanek Kristina, H. Nino, Amir-Asgari Sahand, Hienert Julius, F. Oliver
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摘要

目的:对超声乳化术中有或没有使用撕囊瓣作为额外的内皮保护盾的旋转晶状体碎片进行分类和量化。同时,确定白内障手术中碎片对角膜内皮细胞计数(ECC)和角膜中央厚度(CCT)的影响。方法:将拟行手术的致密性白内障患者随机分为研究组和对照组(2:1)。在研究组中,来自撕囊的前囊“皮瓣”在超声乳化术中用作内皮保护盾。对照组接受标准手术治疗。术中进行光学相干断层扫描,对撞击角膜内皮的旋转晶状体碎片进行评分。分别于手术前后多个时间点测量CCT和ECC。结果:49例患者49只眼中有176块碎片接触到角膜内皮。研究组的平均碎片数为2.8个,对照组为4.8个。两组间ECC差异无统计学意义。术后1天,研究组平均CCT增加16.6µm,对照组平均CCT增加42µm。两组间CCT的增加没有显著差异。结论:与对照组相比,研究组在ECC或CCT方面没有发现明显的益处,这意味着我们无法证明使用撕囊瓣作为保护盾是保护角膜内皮的充分方法。
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Protecting the Corneal Endothelium during Cataract Surgery Using the Anterior Capsulorhexis Flap as a Corneal Protection Shield
Purpose: Classification and quantification of swirling lens fragments during phacoemulsification with or without using the capsulorhexis flap as an additional endothelial protective shield. Also, to determine the effects on endothelial cell count (ECC) and central corneal thickness (CCT) caused by fragments during cataract surgery. Methods: Patients with dense cataracts scheduled for surgery were randomized into study and control groups (2:1). In the study group, the anterior capsule ‘flap’ from the capsulorhexis was used as an endothelial protection shield during phacoemulsification. The control group underwent standard surgery. During surgery, intra-operative optical coherence tomography was performed to score swirling lens fragments that hit the corneal endothelium. CCT and ECC were measured at several time points before and after surgery. Results: In total, 176 fragments in 49 eyes of 49 patients came in contact with the corneal endothelium. The mean number of fragments was 2.8 in the study group and 4.8 in the control group. There was no statistically significant change of ECC between the groups. Mean CCT increased by 16.6 µm in the study group and by 42µm in the control group 1 day postoperatively. There was no significant difference between the groups regarding the increase in CCT. Conclusions: No significant benefit concerning ECC or CCT was found in the study group compared to the control group, meaning that we were not able to prove that using the capsulorhexis flap as a protection shield is a sufficient method of protecting the corneal endothelium.
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