面向神经外科光学导向的扫波长拉曼光谱系统设计

Elahe Parham, Daniel C. Côté
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引用次数: 1

摘要

拉曼光谱已被用于癌症研究和大脑研究中的疾病诊断。本论文的目的是展示一个概念验证,用于高速高信噪比的实时体内拉曼光谱扫描源设置。获得的拉曼光谱可用于区分脑白质和灰质等脑区域,为治疗帕金森病的深部脑刺激神经外科手术提供指导信息。
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Designing a Wavelength-Swept Raman Spectroscopy System for Optical Guidance Neurosurgery
Raman spectroscopy has been used for disease diagnosis in cancer research and brain research. The purpose of the present paper is to show a proof-of-concept for a swept-source setup for real-time in vivo Raman spectroscopy at high speed with high signal to noise ratio. The obtained Raman spectrum could be used to differentiate brain regions such as white and grey matter, providing guidance information during deep brain stimulation neurosurgery to treat Parkinson disease.
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