纳米技术能帮助突破早期癌症诊断的极限吗

M. Agrawal, Abhijit Biswas
{"title":"纳米技术能帮助突破早期癌症诊断的极限吗","authors":"M. Agrawal, Abhijit Biswas","doi":"10.15406/jnmr.2017.05.00100","DOIUrl":null,"url":null,"abstract":"J Nanomed Res 2017, 5(1): 00100 connected with it). Therefore, applications of these techniques are limited due to the lack of sufficient sensitivity to detect small numbers of malignant cells in the primary or even metastatic sites [1]. It is also difficult to detect specific cancer cell-surface markers, which are not only a target for cancer therapy but can also assist in the diagnosis and staging of cancer. Other challenges include inadequate drug concentrations reaching the tumor and the limited ability to monitor therapeutic responses thus leading to significant complications such as multidrug resistance due to poor drug delivery [1].","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Can Nanotechnology help Push the Limit for Early Cancer Diagnostics\",\"authors\":\"M. Agrawal, Abhijit Biswas\",\"doi\":\"10.15406/jnmr.2017.05.00100\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"J Nanomed Res 2017, 5(1): 00100 connected with it). Therefore, applications of these techniques are limited due to the lack of sufficient sensitivity to detect small numbers of malignant cells in the primary or even metastatic sites [1]. It is also difficult to detect specific cancer cell-surface markers, which are not only a target for cancer therapy but can also assist in the diagnosis and staging of cancer. Other challenges include inadequate drug concentrations reaching the tumor and the limited ability to monitor therapeutic responses thus leading to significant complications such as multidrug resistance due to poor drug delivery [1].\",\"PeriodicalId\":16465,\"journal\":{\"name\":\"Journal of Nanomedicine Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Nanomedicine Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/jnmr.2017.05.00100\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nanomedicine Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/jnmr.2017.05.00100","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

纳米材料学报,2017,5(1):00100 [J] .链接本文:因此,由于缺乏足够的灵敏度来检测原发部位甚至转移部位的少量恶性细胞,这些技术的应用受到限制[1]。特异性癌细胞表面标志物的检测也很困难,这些标志物不仅是癌症治疗的靶点,而且还可以帮助癌症的诊断和分期。其他挑战包括到达肿瘤的药物浓度不足以及监测治疗反应的能力有限,从而导致严重的并发症,如由于药物递送不良而产生的多药耐药[1]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Can Nanotechnology help Push the Limit for Early Cancer Diagnostics
J Nanomed Res 2017, 5(1): 00100 connected with it). Therefore, applications of these techniques are limited due to the lack of sufficient sensitivity to detect small numbers of malignant cells in the primary or even metastatic sites [1]. It is also difficult to detect specific cancer cell-surface markers, which are not only a target for cancer therapy but can also assist in the diagnosis and staging of cancer. Other challenges include inadequate drug concentrations reaching the tumor and the limited ability to monitor therapeutic responses thus leading to significant complications such as multidrug resistance due to poor drug delivery [1].
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
A review on saponins from medicinal plants: chemistry, isolation, and determination A uncanny potential of plants for metal nanoparticles synthesis Nanosystems and magnetism Future of graphene in bio-medical application Preparation & evaluation of paracetamol solid lipid nanoparticles by hot homogenization method
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1