新冠肺炎疫苗接种后扁平苔藓2例报告

S. Alotaibi, Ruaa Alharithy, Faisal A Alsharif, Norah Alkhayal
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引用次数: 1

摘要

扁平苔藓是一种t细胞介导的炎症性疾病,可能与预先暴露于包括疫苗、病毒和药物在内的特定介质有关。该疾病的起源尚不清楚,具有不同的临床表现,最近生产的COVID-19疫苗与几种皮肤反应有关,这些反应与COVID-19病毒感染的皮肤表现相似,大多数人在注射第二剂辉瑞疫苗后出现皮肤表现,最近有报告称,在注射辉瑞疫苗后,先前存在的扁平地衣突然出现。我们介绍了两个有趣的病例,他们在辉瑞生物技术公司(Pfizer-BioNTech)的COVID-19疫苗后出现了皮肤病。第一个病例是一名60岁的男性,15年前有扁平苔藓的病史,经过局部治疗和控制成功,在服用辉瑞生物技术公司的COVID-19疫苗后突然发作。第二例为57岁女性,既往高血压和甲状腺功能减退病史得到控制。在接种第三剂COVID - 19疫苗后出现新的扁平苔藓。第三次注射后3周出现病变。
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Lichen planus after COVID-19 vaccination: A report of two cases
Lichen planus is a T-cell-mediated inflammatory disease that can be associated with preexposure to particular agents encompassing vaccines, viruses, and drugs. The origin of the disease is unknown and has varying clinical presentations, the recent manufactured COVID-19 vaccines have been linked with several cutaneous reactions that are similar to the cutaneous manifestations of COVID-19 virus infection, the majority of people developed cutaneous manifestations after the second dose of Pfizer vaccine, recent cases have been reported as a flare of a preexisting lichen planus following the administering of the Pfizer vaccine. We present a two interesting cases that developed a dermatological condition post Pfizer-BioNTech's COVID-19 vaccine. The first case is a 60-year-old man, with a past medical history of having lichen planus 15 years ago, that have been treated and controlled successfully with topical therapy, flared up following the administration of Pfizer-BioNTech's COVID-19 vaccine. The second case is a 57-year-old female with a past medical history of hypertension and hypothyroidism controlled. Develop the new onset of lichen planus after receiving the third dose of the COVID 19 vaccine. The lesions arise 3 weeks after the third dose.
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