在没有心脏外科的医院进行经导管主动脉瓣介入治疗:未来的前景?

IF 1 4区 综合性期刊 Q3 MULTIDISCIPLINARY SCIENCES Interdisciplinary Science Reviews Pub Date : 2024-04-01 Epub Date: 2022-06-10 DOI:10.23736/S2724-5683.22.06076-8
Stefano Rigattieri, Chiara Bernelli, Francesco Tomassini, Giorgio Caretta, Shahram Moshiri, Andrea Berni, Ferdinando Varbella, Alberto Menozzi
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引用次数: 0

摘要

经导管主动脉瓣介入术(TAVI)于 2000 年初问世,为无法手术的严重主动脉瓣狭窄患者提供治疗。几十年后,该手术对中低手术风险患者也变得有效和安全;因此,由于人口逐渐老龄化,对经导管主动脉瓣介入手术的临床需求不断增加,而手术的可用性(即所谓的 "TAVI 容量")却难以满足这种需求。因此,许多患者在转诊至 TAVI 中心时遇到困难,或面临漫长的候诊时间,从而有可能在手术实施前发生严重的不良事件(包括死亡)。尽管当代指南和共识文件建议,TAVI 只应在设有心脏外科的医院进行,但在没有心脏外科的心脏介入实验室也开展 TAVI 项目,不失为一种提高 TAVI 容量的方法,从而使更多患者在更短的时间内得到治疗。但从另一个角度来看,这种策略可能会危及患者的安全,因为一旦出现围手术期并发症,就需要进行救助手术,并可能导致多学科心脏团队的评估效果不理想。本综述旨在评估和讨论现有的临床数据,以及考虑到日益增长的未满足临床需求和 TAVI 平台的技术进步,在未设立心脏外科的医院实施 TAVI 项目的情况,同时也不忽视国际科学协会的建议。
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Transcatheter aortic valve intervention in hospitals without cardiac surgery departments: a future scenario?

Transcatheter aortic valve intervention (TAVI) was introduced in early 2000 to offer treatment to inoperable patients with severe aortic valve stenosis. In a couple of decades, the procedure resulted effective and safe also in patients with intermediate to low risk for surgery; therefore, due to the progressive ageing of the population, the clinical need for TAVI is continuously increasing and is hardly met by the availability of the procedure, the so-called "TAVI capacity". As a result, many patients encounter difficulties in being referred to TAVI centers or face long waiting list times, thus risking severe adverse events (including death) before the procedure is performed. Although contemporary guidelines and consensus documents recommend that TAVI should only be performed in hospitals with active cardiac surgery departments, starting TAVI programs also in interventional cardiac laboratories without on-site cardiac surgery could represent a way to increase TAVI capacity, thus leading to a greater number of patients being treated in less time. On the other side of the coin, such a strategy may jeopardize patient safety in case of periprocedural complications needing bailout surgery and may lead to a suboptimal multidisciplinary Heart Team evaluation. This review aims to assess and discuss available clinical data and implementation of TAVI programs in hospitals without on-site active cardiac surgery departments considering the growing unmet clinical need and technical advancement of TAVI platforms, yet not overlooking the recommendations of international scientific societies.

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来源期刊
Interdisciplinary Science Reviews
Interdisciplinary Science Reviews 综合性期刊-综合性期刊
CiteScore
2.30
自引率
9.10%
发文量
20
审稿时长
>12 weeks
期刊介绍: Interdisciplinary Science Reviews is a quarterly journal that aims to explore the social, philosophical and historical interrelations of the natural sciences, engineering, mathematics, medicine and technology with the social sciences, humanities and arts.
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