风湿性三尖瓣疾病:修复与置换

Ahmed M. Elwakeel, A. E. El Midany, I. N. El-Sokkary, M. Mahmoud, Bahaa A. Elkhonezy, Haytham M. Abdelmoaty, Mohammed Wael Badawi, T. Hikal, M. Ahmed, A. Khaled, Mohammed E. ElSaid, Ibrahim K. Gamil, Mahmoud khadrawy, Mahmoud M. Elwakeel, Eman Mahmoud, Ahmed H. Lamloom
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摘要

背景:三尖瓣疾病最常见的是功能性疾病,然而,器质性疾病仍占病例的四分之一。在埃及流行的风湿热是器质性疾病的主要原因。目前的做法很大程度上依赖于三尖瓣修复;然而,确定最佳的手术程序一直很困难。目的:在此,我们研究了这类患者的置换与修复的结果。患者和方法:在2014年至2018年期间,对300例连续接受三尖瓣手术且三尖瓣严重受损的风湿性心脏病患者进行了一项前瞻性研究。患者分为两组;TVR组(n=150)包括三尖瓣置换术患者,TVR组(n=150)包括三尖瓣修复术患者。超声心动图诊断及随访。记录围手术期变量、临床结果、发病率、死亡率和随访数据。结果:平均随访4±1.32年。TVR组住院死亡率6例(4%),TVR组住院死亡率3例(2%)(P值≥0.05)。术后低心输出量综合征和卒中发生率明显高于修复组。术后右心室功能障碍、肾功能损害、肾功能衰竭和胸部再探查发生率明显高于替代组。修复组随访19例(12.6%)出现严重三尖瓣反流。结论:三尖瓣修复术优于置换术,避免了假体的弊端。然而,三尖瓣置换术是可行的,生存率相当,风湿性疾病的进行性可能推荐置换术。
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Rheumatic tricuspid valve disease: Repair versus Replacement
Background : Tricuspid valve disease is most commonly functional, however, organic affection still accounts for one fourth of cases. Rheumatic fever which is endemic in Egypt is a main cause of organic affection. Current practice largely relies on tricuspid valve repair; however, it has been difficult to determine optimal procedure. Objectives : Herein, we study the outcome of replacement versus repair in such patients. Patients and methods : A prospective study was conducted on 300 consecutive patients with rheumatic heart disease showing severe tricuspid valve affection underwent tricuspid valve surgery, between 2014 and 2018. The patients were divided into two groups; TVR group (n=150) which included patients who underwent tricuspid valve replacement and TVr group (n=150) which included patients who underwent tricuspid valve repair. Diagnosis and follow up were done by echocardiography. Peri-operative variables, clinical outcome, morbidity, mortality, and follow up data were recorded. Results: Mean follow-up was 4±1.32 years. In-hospital mortality was 6 patients (4%) in TVR group and 3 patients (2%) in TVr group (P value ≥ 0.05). Postoperative low cardiac output syndrome and stroke were significantly higher in the repair group. Postoperative RV dysfunction, renal impairment, renal failure and chest re-exploration were significantly higher in the replacement group. Severe tricuspid regurgitation was reported in 19 patients (12.6%) of the repair group on follow up. Conclusion : Tricuspid valve repair is preferable to replacement to avoid the drawbacks of prosthesis. However, tricuspid valve replacement is feasible with comparable survival outcome and the progressive nature of the rheumatic disease may recommend replacement.
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