{"title":"雌性大鼠青春期卵巢结构的组织学特征","authors":"N. A. Dudenkova, O. Shubina, V. S. Bardin","doi":"10.35679/1991-9476-2021-16-6-752-761","DOIUrl":null,"url":null,"abstract":"The relevance of our study is due to the high frequency and prevalence of such a female disease as infertility, which can lead to various developments of fetal pathologies. All this can be incorporated in the very nature of germ cells, but also arise in the course of their formation and maturation. The aim of this study is to study the histological parameters of the ovaries of nulliparous white rats in the postnatal period. As an object of study in our work, we used female white sexually mature rats of the line at the age of 2–3 months and weighing about 200–250 g. The rats were kept in a standard vivarium and were not subjected to pathological effects. The material of histological examination was the ovaries at the stage of diestrus. Smears and tissue samples were examined using an Axio Imager.M2 digital microscope (ZEISS, Japan) with AxioVision SE64 Rel image analysis software. 4.8.3 and ZEN 2011. In the course of our studies, we noted that at the stage of diestrus in the ovarian cortex, follicles are at different stages of development: from primordial follicles and up to mature graphite vesicles. Atretic follicles are also revealed. The connective tissue stroma forms the basis of the ovary and is located between the follicles. In the ovaries of female white rats, yellow bodies of menstruation were found, which always form after ovulation of a mature mature follicle. The detected menstrual corpus luteum in the cortical substance of the ovary are evenly distributed. The revealed histological features of the structure of the ovaries of female white rats prove the sexual maturity of the experimental animals.","PeriodicalId":14015,"journal":{"name":"International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"HISTOLOGICAL FEATURES OF THE STRUCTURE OF THE OVARIES OF FEMALE WHITE RATS DURING PUBERTY\",\"authors\":\"N. A. Dudenkova, O. Shubina, V. S. Bardin\",\"doi\":\"10.35679/1991-9476-2021-16-6-752-761\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The relevance of our study is due to the high frequency and prevalence of such a female disease as infertility, which can lead to various developments of fetal pathologies. All this can be incorporated in the very nature of germ cells, but also arise in the course of their formation and maturation. The aim of this study is to study the histological parameters of the ovaries of nulliparous white rats in the postnatal period. As an object of study in our work, we used female white sexually mature rats of the line at the age of 2–3 months and weighing about 200–250 g. The rats were kept in a standard vivarium and were not subjected to pathological effects. The material of histological examination was the ovaries at the stage of diestrus. Smears and tissue samples were examined using an Axio Imager.M2 digital microscope (ZEISS, Japan) with AxioVision SE64 Rel image analysis software. 4.8.3 and ZEN 2011. In the course of our studies, we noted that at the stage of diestrus in the ovarian cortex, follicles are at different stages of development: from primordial follicles and up to mature graphite vesicles. Atretic follicles are also revealed. The connective tissue stroma forms the basis of the ovary and is located between the follicles. In the ovaries of female white rats, yellow bodies of menstruation were found, which always form after ovulation of a mature mature follicle. The detected menstrual corpus luteum in the cortical substance of the ovary are evenly distributed. The revealed histological features of the structure of the ovaries of female white rats prove the sexual maturity of the experimental animals.\",\"PeriodicalId\":14015,\"journal\":{\"name\":\"International Journal of Life-Sciences Scientific Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Life-Sciences Scientific Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.35679/1991-9476-2021-16-6-752-761\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Life-Sciences Scientific Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35679/1991-9476-2021-16-6-752-761","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
HISTOLOGICAL FEATURES OF THE STRUCTURE OF THE OVARIES OF FEMALE WHITE RATS DURING PUBERTY
The relevance of our study is due to the high frequency and prevalence of such a female disease as infertility, which can lead to various developments of fetal pathologies. All this can be incorporated in the very nature of germ cells, but also arise in the course of their formation and maturation. The aim of this study is to study the histological parameters of the ovaries of nulliparous white rats in the postnatal period. As an object of study in our work, we used female white sexually mature rats of the line at the age of 2–3 months and weighing about 200–250 g. The rats were kept in a standard vivarium and were not subjected to pathological effects. The material of histological examination was the ovaries at the stage of diestrus. Smears and tissue samples were examined using an Axio Imager.M2 digital microscope (ZEISS, Japan) with AxioVision SE64 Rel image analysis software. 4.8.3 and ZEN 2011. In the course of our studies, we noted that at the stage of diestrus in the ovarian cortex, follicles are at different stages of development: from primordial follicles and up to mature graphite vesicles. Atretic follicles are also revealed. The connective tissue stroma forms the basis of the ovary and is located between the follicles. In the ovaries of female white rats, yellow bodies of menstruation were found, which always form after ovulation of a mature mature follicle. The detected menstrual corpus luteum in the cortical substance of the ovary are evenly distributed. The revealed histological features of the structure of the ovaries of female white rats prove the sexual maturity of the experimental animals.