光谱域光学相干断层扫描测量不同折射状态患者脉络膜厚度

Farhat Abrar, Juhi Garg, Shashwat Singh, Kainat Chaudhary
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摘要

目的:评价光谱域光学相干断层扫描对不同折射状态患者脉络膜厚度的影响。材料与方法:本横断面观察性研究随机选取60名在印度密鲁特Chattrapati Shivaji Subharti医院眼科门诊就诊的患者,时间为1年。根据屈光不正将受试者分为三组:屈光不正+1或以上的受试者被分为远视组;视屈光度< +1 > -1者为远视组;屈光度为-1或更低的人被分配到近视组。所有患者均接受了临床病史和完整的眼科检查。使用Optovue RTvue 100进行OCT扫描,该仪器利用光谱域(SD)-OCT。增强深度成像(EDI)技术显示脉络膜。使用光谱域光学相干断层扫描(SD-OCT)增强深度成像(EDI)获得所有眼睛的脉络膜扫描。数据以excel表格记录,并进行统计分析。结果:与非远视者相比,近视眼受试者在所有区域的脉络膜都明显变薄。远视受试者的脉络膜在大多数地区明显厚于正视受试者。线性相关测试显示,所有区域的屈光不正与脉络膜厚度密切相关。结论:高度近视眼视网膜各点的脉络膜均明显薄于正视对照,其中距中央窝1.5 mm处的脉络膜最薄。
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Choroidal thickness in patients with different refractive status measured by spectral-domain optical coherence tomography
Aim: To evaluate the choroidal thickness in patients with different refractive status measured by spectral-domain optical coherence tomography. Material and methods: This cross-sectional observational study consisted of 60 subjects, who visited the out-patient department of Ophthalmology, Chattrapati Shivaji Subharti Hospital, Meerut, India and were randomly selected over a period of 1 year. Subjects were classified into three groups based on refractive error: those with a +1 diopter or greater refractive power were assigned to the hyperopia group; those with a diopter lower than +1 and greater than –1 were assigned to the emmetropia group; and those with a –1 diopter or lower diopter were assigned to the myopia group. All patients underwent a clinical history taking and a complete ophthalmic examination. OCT scanning was performed using Optovue RTvue 100 which utilises spectral domain (SD)-OCT. The choroid was visualized by enhanced depth imaging (EDI) technique. Choroidal scans were obtained for all the eyes using enhanced depth imaging (EDI) using spectral-domain optical coherence tomography (SD-OCT). Data was recorded in excel sheet and subjected to statistical analysis. Results: Compared to emmetropic participants, myopic subjects had significantly thinner choroid in all the regions. Choroid of hyperopic subjects was significantly thicker than that of emmetropic subjects in most regions. Linear correlation testing revealed a close correlation between refractive error and choroidal thickness in all of the regions. Conclusion: High myopes have significantly thinner choroids than the emmetropic controls at all the retinal points studied, with the thinnest choroid at 1.5 mm nasal to the fovea.
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