脱发的先进方法

A. Mohan, M. Khan, S. Chandra
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引用次数: 4

摘要

脱发的特点是头发主要在头皮上脱落,有时会在身体的其他部位脱落,对患者有负面的心理和社会影响。雄激素性脱发和斑秃是常见的疾病。雄激素性脱发是头皮毛囊对双氢睾酮的敏感性,斑秃是一种自身免疫性疾病。目前的研究已经解释了皮质类固醇治疗或紫外线A治疗与全身皮质类固醇联合治疗严重AA的疗效。非那雄胺为治疗雄激素性脱发开辟了新的可能性。目前的药物治疗方法使用再生刺激剂,如米诺地尔和非那雄胺治疗雄激素性脱发,以及皮质类固醇、PUVA治疗斑秃。针对毛囊单位的靶向递送有助于更快地靶向细胞,通过更快地获得药物,加速药物作用,新的联合治疗方法,如维甲酸与米诺地尔的联合治疗效果更好,基因治疗是处于开发阶段的新方法,在动物和人类身上都取得了令人满意的结果。
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Advance approaches in alopecia
Alopecia is characterized by hair loss mainly on scalp some time on other resign of the body that has negative psychological and social impact on patients. Androgenetic alopecia and alopecia areata are common disorders. Androgenetic alopecia is the sensitivity of scalp follicles to dihydrotestosterone and alopecia areata is an autoimmune disorder. Current studies have explained the efficacy of corticosteroid therapy or the combination of ultraviolet A therapy and systemic corticosteroids for severe AA. Finasteride opens up new possibilities for the treatment of androgenetic alopecia. Current drug treatment approaches use regrowth stimulators such as minoxidil and finasteride for androgenetic alopecia, as well as corticosteroids, PUVA therapy for alopecia areata. Targeted delivery to the Hair follicle units helps faster targeting to cells that accelerate drug action by faster availability of drug, novel combination treatments combinations like tretinoin with minoxidil shows better results, gene therapy are new approaches that are under developing stage and giving satisfactory results on animal as well as humans.
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