继发于肺结核的视网膜闭塞性血管炎-一份临床报告

Irina Ramos Gomes, V. Nogueira
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摘要

目的:报告一例继发于结核性视网膜闭塞性血管炎并发持续性右眼玻璃体粘连的病例。方法:男性患者,35岁,印度裔,既往无全身性疾病史。首次出现在我们的门诊,视力下降,持续8个月。检查时BCVA RE: <5/200, BCVA LE: 20/20;可见角状沉淀,前房光斑为1+;广泛的RE玻璃体妨碍了眼底观察。LE的荧光素血管造影(FA)正常。他开始局部使用类固醇,并接受玻璃体切除+术中视网膜光凝术,以建立周围视网膜新生血管。结果:术后检查,BCVA RE: 20/100, BCVA LE: 20/20,双侧无前房反应。RE型黄斑水肿伴大量血管肿大和“鬼血管”。FA在RE上证实活动性闭塞性血管炎。诊断性检查28毫米硬化结核菌素试验阳性,支持眼结核的诊断。病人开始服用抗结核药物。3个月后,BCVA RE为20/25,无前房反应OU。18个月后,患者保持良好的双侧视力,无任何疾病复发的迹象。结论:在本病例中,患者在接受抗结核治疗后反应良好,视力得到改善,炎症性血管造影征象得到缓解,强调了视网膜血管炎病例中结核病因学研究的重要性。
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RETINAL OCCLUSIVE VASCULITIS SECONDARY TO TUBERCULOSIS – A CLINICAL REPORT
Purpose: To report the case of a patient with persistent right eye (RE) hemovitreous secondary to occlusive retinal vasculitis secondary to tuberculosis. Methods: Male patient, 35 years old, Indian descent, with no history of previous systemic illness. First presented to our outpatient clinic with decreased visual acuity RE with 8 months duration. On exam, BCVA RE: <5/200 and BCVA LE: 20/20; keratic precipitates were visible and anterior chamber flare was described as 1+; extensive RE hemovitreous were present precluding fundus observation. A fluorescein angiography (FA) performed on his LE was normal. He was started on topical steroids and submitted to pars plana vitrectomy + intra-operative retinal photocoagulation on his RE for peripheral retinal neovascularization. Results: Post-surgery exam, BCVA RE: 20/100 and BCVA LE: 20/20, no anterior chamber reaction bilaterally. RE macular edema with exuberant vascular turtuosity and “ghost vessels”. FA confirmed active occlusive vasculitis on RE. Diagnostic work-up was positive for a 28 mm induration tuberculin test, supporting the diagnosis of ocular tuberculosis. The patient was started on anti-tuberculous medication. Three months later, BCVA RE was 20/25 with no anterior chamber reaction OU. Eighteen months on, the patient maintains good bilateral visual acuity without any evidence of disease reactivation. Conclusions: In the clinical case described there was a good response after antituberculosis treatment instituted unassociated oral corticosteroid therapy, with improved visual acuity and remission of inflammatory angiographic signs, stressing the importance of tuberculous etiology research in cases of retinal vasculitis.
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