支气管哮喘与肥胖相关的心血管和心血管代谢风险分析

D. Anikin, I. Solovyeva, I. Demko, E. Sobko, N. Gordeeva, A. Kraposhina
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引用次数: 0

摘要

支气管哮喘和肥胖症在世界范围内的发病率稳步上升,给社会造成重大经济损失。毫无疑问,肥胖在心血管事件发生中的致病作用。目的是分析目前的数据,证明哮喘和肥胖关联对心血管疾病风险增加的影响。肥胖的关键作用被认为是支气管哮喘和心血管疾病发生和发展的危险因素。该综述强调了根据临床指南中规定的普遍接受的量表确定心血管和心血管代谢风险的重要性。作为综述的一部分,我们分析了支气管哮喘和心血管疾病的合并,并指出了它们的发病相互依赖性。脂肪组织代谢过程的作用显示,它可以增加支气管哮喘的炎症和导致心血管疾病的进展。了解相互影响的机制将有助于个性化治疗,以及预防支气管哮喘和肥胖患者的心血管事故。
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Analysis of cardiovascular and cardiometabolic risks in the association of bronchial asthma and obesity
Bronchial asthma and obesity are showing a steady increase in incidence worldwide, incurring significant economic losses for society. There is no doubt about the pathogenetic role of obesity in the development of cardiovascular events. The purpose is to analyze the current data that demonstrate the impact of asthma and obesity association on the increased risk of cardiovascular disease. The critical role of obesity is noted as a risk factor for the development and progression of both bronchial asthma and cardiovascular diseases. The review emphasizes importance of determining cardiovascular and cardiometabolic risks according to generally accepted scales specified in clinical guidelines. As part of the review, the combination of bronchial asthma and cardiovascular diseases was analyzed, and their etiopathogenetic interdependence was noted. The role of metabolic processes in adipose tissue is shown, which can increase both inflammation in bronchial asthma and lead to the progression of cardiovascular diseases. Understanding the mechanisms of mutual influence will allow for personalized treatment, as well as the prevention of cardiovascular accidents in patients with bronchial asthma and obesity.
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