Pub Date : 2023-01-01DOI: 10.32000/2072-1757-2023-3-19-23
E. Mendelevich, A. A. Kurbanova
The article presents a review of literature devoted to a variant of cavity formation in spinal cord — hydromyelia. The authors review the history of studying the issue referring to the central canal expansion and list the main theories of hydromyelic cavities formation based on anatomical ideas about the central canal structure and functioning. The review describes the criteria of hydromyelic cavities diagnosis, clinical and MR-tomographic course of hydromyelia. In addition, cases of hydromyelia combination with other pathological conditions are presented.
{"title":"Hydromyelia: evolution of ideas and diagnostic criteria","authors":"E. Mendelevich, A. A. Kurbanova","doi":"10.32000/2072-1757-2023-3-19-23","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-19-23","url":null,"abstract":"The article presents a review of literature devoted to a variant of cavity formation in spinal cord — hydromyelia. The authors review the history of studying the issue referring to the central canal expansion and list the main theories of hydromyelic cavities formation based on anatomical ideas about the central canal structure and functioning. The review describes the criteria of hydromyelic cavities diagnosis, clinical and MR-tomographic course of hydromyelia. In addition, cases of hydromyelia combination with other pathological conditions are presented.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73551654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32000/2072-1757-2023-3-146-149
K. Shaporeva, S. Lapshina, E. Sukhorukova, A. Garaeva, R. Abdrakipov, D. Abdulganieva
This article presents a clinical case of a patient with a mixed connective tissue disease. The clinical picture in the debut was polymorphic, the patient had arthritis, skin lesions, general inflammation, myopathy, Raynaud’s syndrome, dysphagia, angio-neurotic edema. The immunological panel reflected the presence of antibodies characteristic of autoimmune diseases (antinuclear antibodies, antibodies to ribonucleoprotein, antimitochondrial antibodies, antibodies to cytoplasmic antigen SS-B). Glucocorticosteroids (GCS), immunosuppressive drugs (metatrexate, sulfasalazine, hydroxychloroquine, azathioprine) were used as starting therapy, but the disease progressed. Pulse therapy of GCS and plasmapheresis did not give a positive result. We used Rituximab, because the pathogenesis of the disease was characterized by the activation of B-cells. Currently, two infusions have been performed, positive dynamics has been noted. Thus, the therapy of mixed connective tissue disease creates many diagnostic and therapeutic problems in clinical practice.
{"title":"Sharpe’s syndrome: from basic anti-inflammatory therapy to genetically engineered biological drugs","authors":"K. Shaporeva, S. Lapshina, E. Sukhorukova, A. Garaeva, R. Abdrakipov, D. Abdulganieva","doi":"10.32000/2072-1757-2023-3-146-149","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-146-149","url":null,"abstract":"This article presents a clinical case of a patient with a mixed connective tissue disease. The clinical picture in the debut was polymorphic, the patient had arthritis, skin lesions, general inflammation, myopathy, Raynaud’s syndrome, dysphagia, angio-neurotic edema. The immunological panel reflected the presence of antibodies characteristic of autoimmune diseases (antinuclear antibodies, antibodies to ribonucleoprotein, antimitochondrial antibodies, antibodies to cytoplasmic antigen SS-B). Glucocorticosteroids (GCS), immunosuppressive drugs (metatrexate, sulfasalazine, hydroxychloroquine, azathioprine) were used as starting therapy, but the disease progressed. Pulse therapy of GCS and plasmapheresis did not give a positive result. We used Rituximab, because the pathogenesis of the disease was characterized by the activation of B-cells. Currently, two infusions have been performed, positive dynamics has been noted. Thus, the therapy of mixed connective tissue disease creates many diagnostic and therapeutic problems in clinical practice.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73846338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32000/2072-1757-2023-3-96-104
O. Khayrutdinova, E. Bogdanov
The article considers the relation between clinical manifestations of central sensitization (CS) and the course of episodic migraine as an independent nosology and combined with cervicalgia or cervicogenic headache. The research objective was to study the comorbid pathologies in patients with episodic migraine, characteristic for central sensitization — anxiety, depression, cervicalgia, cervicogenic headache, and sleep disorders. We found the relationship between the intensity of migraine pain syndrome, migraine duration in anamnesis, and the central sensitization index — CSI. At the same time, the CS intensity also directly depended on the number of involved muscles and triggers. The effect was shown of the cervicogenic factor as a predictor or trigger in patients with migraine and cervicogenic headache, as well as the significant impact of clinical manifestations of CS on the quality of life of patients with episodic migraine.
{"title":"Clinical manifestations of central sensitization in patients with episodic migraine combined with active cervicalgic component","authors":"O. Khayrutdinova, E. Bogdanov","doi":"10.32000/2072-1757-2023-3-96-104","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-96-104","url":null,"abstract":"The article considers the relation between clinical manifestations of central sensitization (CS) and the course of episodic migraine as an independent nosology and combined with cervicalgia or cervicogenic headache. The research objective was to study the comorbid pathologies in patients with episodic migraine, characteristic for central sensitization — anxiety, depression, cervicalgia, cervicogenic headache, and sleep disorders. We found the relationship between the intensity of migraine pain syndrome, migraine duration in anamnesis, and the central sensitization index — CSI. At the same time, the CS intensity also directly depended on the number of involved muscles and triggers. The effect was shown of the cervicogenic factor as a predictor or trigger in patients with migraine and cervicogenic headache, as well as the significant impact of clinical manifestations of CS on the quality of life of patients with episodic migraine.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74472775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32000/2072-1757-2023-1-8-10
N. Korotaeva, L. I. Ippolitova, E. Pershina
Bone mineralization is significantly smaller in preterm infants than in full-term infants. This poses a risk of a frequent complication — preterm infant osteopenia. Despite improvements in approaches to nutritional support and standard care, osteopenia is still a problem affecting at least 20% of preterm infants discharged from hospitals. The article presents a systematic review of the modern evidences related to the impact of early physical activity and massage on the prevention and treatment of osteopenia in this group of patients.
{"title":"New opportunities for prevention of osteopenia in preterm infants","authors":"N. Korotaeva, L. I. Ippolitova, E. Pershina","doi":"10.32000/2072-1757-2023-1-8-10","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-1-8-10","url":null,"abstract":"Bone mineralization is significantly smaller in preterm infants than in full-term infants. This poses a risk of a frequent complication — preterm infant osteopenia. Despite improvements in approaches to nutritional support and standard care, osteopenia is still a problem affecting at least 20% of preterm infants discharged from hospitals. The article presents a systematic review of the modern evidences related to the impact of early physical activity and massage on the prevention and treatment of osteopenia in this group of patients.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74525967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32000/2072-1757-2023-3-141-145
I. M. Sadreeva, A. A. Sadreeva, A. V. Maksimov
The antiphospholipid syndrome (APS) is characterized by non-inflammatory thrombotic vasculopathy with lesions of vessels of all types and localization. That is why clinical manifestations of APS are varied and patients turn to various physicians. The article describes a clinical case of a critical lower limb ischemia in AP. A 62 y. o. female patient was under outpatient observation for two years with the clinic of intermittent claudication and a diagnosis of atherosclerosis of lower limb arteries. At the same time, a history of thrombosis of the splenic artery — atypical for atherosclerosis, laboratory phenomena: a false-positive Wassermann reaction and an elongation of the phospholipid-dependent test (APTT) indicated APS. The patient was admitted into Department of Vascular Surgery of the Republic Clinical Hospital with critical lower limb ischemia and a threat of amputation. Antiphospholipid antibodies were detected. Due to the therapy pathogenetic for APS, amputation of the lower extremity was avoided. The presented clinical case shows that the APS may occur in people older than 60, and physicians of all specialties should be alert to this diagnosis.
{"title":"Clinical case of successful treatment of a patient with critical lower limb ischemia as a late onset of antiphospholipid syndrome","authors":"I. M. Sadreeva, A. A. Sadreeva, A. V. Maksimov","doi":"10.32000/2072-1757-2023-3-141-145","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-141-145","url":null,"abstract":"The antiphospholipid syndrome (APS) is characterized by non-inflammatory thrombotic vasculopathy with lesions of vessels of all types and localization. That is why clinical manifestations of APS are varied and patients turn to various physicians. The article describes a clinical case of a critical lower limb ischemia in AP. A 62 y. o. female patient was under outpatient observation for two years with the clinic of intermittent claudication and a diagnosis of atherosclerosis of lower limb arteries. At the same time, a history of thrombosis of the splenic artery — atypical for atherosclerosis, laboratory phenomena: a false-positive Wassermann reaction and an elongation of the phospholipid-dependent test (APTT) indicated APS. The patient was admitted into Department of Vascular Surgery of the Republic Clinical Hospital with critical lower limb ischemia and a threat of amputation. Antiphospholipid antibodies were detected. Due to the therapy pathogenetic for APS, amputation of the lower extremity was avoided. The presented clinical case shows that the APS may occur in people older than 60, and physicians of all specialties should be alert to this diagnosis.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"216 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75606678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32000/2072-1757-2023-3-67-70
A. Y. Teregulov, A. A. Kirshin, A. R. Kirshina, M. Valeev, E. T. Teregulova
False postoperative visceral aneurysms are extremely rare in the clinical practice. Often false aneurysms are a diagnostic finding, and after discharge from the hospital, the patient is exposed to an extreme risk of rupture and death. We present our own observation of successful verification and endovascular correction of pseudoaneurysm of truncus coeliacus after surgical treatment of cancer of the distal part of the common bile duct.
{"title":"Clinical case of successful endovascular treatment of the false aneurysm of truncus coeliacus with the formation of an arteriovenous fistula after pancreatoduodenal resection","authors":"A. Y. Teregulov, A. A. Kirshin, A. R. Kirshina, M. Valeev, E. T. Teregulova","doi":"10.32000/2072-1757-2023-3-67-70","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-67-70","url":null,"abstract":"False postoperative visceral aneurysms are extremely rare in the clinical practice. Often false aneurysms are a diagnostic finding, and after discharge from the hospital, the patient is exposed to an extreme risk of rupture and death. We present our own observation of successful verification and endovascular correction of pseudoaneurysm of truncus coeliacus after surgical treatment of cancer of the distal part of the common bile duct.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74843189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32000/2072-1757-2023-3-154-157
D. Abdulganieva, I. Soloveva, K. M. Sadykova, L. K. Bombina
The article is devoted to the 100th anniversary of Professor R. Sh. Abdrakhmanova, Head of the Department of Faculty Therapy at Kazan State Medical Institute in 1971–1982. Raisa Sharafutdinovna participated in the organization of therapy and rheumatology services in the Republic of Tatarstan. Together with Kazan Medfizpribor Company, she developed and introduced into practice a series of diagnostic devices. Furthermore, R.Sh. Abdrakhmanova was an honored scientist, the author of more than 100 scientific papers and an outstanding doctor. She was a leading freelance pulmonologist of the Republic of Tatarstan and an excellent teacher and mentor. Professor Abdrakhmanova devoted her entire life to medicine. Most part of her labor activity was connected with the Republic Clinical Hospital. Raisa Sharafutdinovna was a highly qualified professional and an outstanding scientist; she left a rich academic legacy and a bright memory among colleagues, department staff and patients.
{"title":"To the 100th anniversary of Professor of Kazan State Medical University R.Sh. Abdrakhmanova","authors":"D. Abdulganieva, I. Soloveva, K. M. Sadykova, L. K. Bombina","doi":"10.32000/2072-1757-2023-3-154-157","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-154-157","url":null,"abstract":"The article is devoted to the 100th anniversary of Professor R. Sh. Abdrakhmanova, Head of the Department of Faculty Therapy at Kazan State Medical Institute in 1971–1982. Raisa Sharafutdinovna participated in the organization of therapy and rheumatology services in the Republic of Tatarstan. Together with Kazan Medfizpribor Company, she developed and introduced into practice a series of diagnostic devices. Furthermore, R.Sh. Abdrakhmanova was an honored scientist, the author of more than 100 scientific papers and an outstanding doctor. She was a leading freelance pulmonologist of the Republic of Tatarstan and an excellent teacher and mentor. Professor Abdrakhmanova devoted her entire life to medicine. Most part of her labor activity was connected with the Republic Clinical Hospital. Raisa Sharafutdinovna was a highly qualified professional and an outstanding scientist; she left a rich academic legacy and a bright memory among colleagues, department staff and patients.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"225 1-2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72681372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32000/2072-1757-2023-3-71-74
A. Y. Teregulov, L. Teregulova, F. F. Minnullina, M. B. Yakovlev, D. P. Dosmanova
Ovarian artery aneurysm rupture is a rare pathology that poses a life-threatening risk when it ruptures. The article presents a literature review of the Pubmed sources on this problem. We also present a clinical case of endovascular treatment of ovarian artery aneurysm rupture in a postpartum patient with a retroperitoneal hematoma as a final result.
{"title":"A case of endovascular treatment of ovarian artery aneurysm rupture in a postpartum patient","authors":"A. Y. Teregulov, L. Teregulova, F. F. Minnullina, M. B. Yakovlev, D. P. Dosmanova","doi":"10.32000/2072-1757-2023-3-71-74","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-71-74","url":null,"abstract":"Ovarian artery aneurysm rupture is a rare pathology that poses a life-threatening risk when it ruptures. The article presents a literature review of the Pubmed sources on this problem. We also present a clinical case of endovascular treatment of ovarian artery aneurysm rupture in a postpartum patient with a retroperitoneal hematoma as a final result.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80038626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32000/2072-1757-2023-1-24-29
G. A. Ignatenko, Y. Lutsenko, A. Bagriy
The purpose — to improve the effectiveness of treatment of diabetic foot patients with cardiovascular disorders. Material and methods. 782 patients with diabetic foot (DF) were under observation. 4 groups were identified: group 1 — VAC therapy was used; group 2 — ultrasonic cavitation; group 3 — modern dressings were used for treatment; group 4 — with a standard treatment. Low doses of statins were used (atorvastatin 10–20 mg/day or rosuvastatin 5–10 mg/day) in 213 patients (27.2%) and 89 patients (11.4%) received moderate or high doses of statins (atorvastatin 40–80 mg/day or rosuvastatin 20 mg/day) in combination with ursodeoxycholic acid (UDCA) preparations (750–1750 mg/day). Results. In the low-dose statin subgroup, the rate of low-density lipoprotein cholesterol levels reduction averaged 17.6 (5.6) % of the initial values; triglycerides, respectively, 12.3 (3.5) % of the initial values; that was statistically significantly lower than in the moderate/high dose statin plus UDCA subgroup of 32.9 (5.4) % and 18.7 (3.2) %, respectively, all p<0.001. In group 1, the average duration of hospital stay and the percentage of postoperative complications were statistically significantly lower in patients who received lipid-lowering therapy (28.5 (3.6) days and 8.8 (2.9) %), compared with those who did not receive this treatment (34.0 (2.8) days and 13.1 (2.6) %); p < 0.001. Similar differences in the length of hospital stay and the percentage of postoperative complications, depending on the lipid-lowering therapy, also occurred in groups 2, 3, and 4 (p < 0.001). Conclusions. The use of lipid-lowering therapy, including moderate / high doses of statins in combination with UDCA, contributed to a decrease in the length of hospital stay and a decrease in the incidence of postoperative complications in all groups of patients with DF.
{"title":"Features of cardiovascular disorders in patients with diabetic foot","authors":"G. A. Ignatenko, Y. Lutsenko, A. Bagriy","doi":"10.32000/2072-1757-2023-1-24-29","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-1-24-29","url":null,"abstract":"The purpose — to improve the effectiveness of treatment of diabetic foot patients with cardiovascular disorders. Material and methods. 782 patients with diabetic foot (DF) were under observation. 4 groups were identified: group 1 — VAC therapy was used; group 2 — ultrasonic cavitation; group 3 — modern dressings were used for treatment; group 4 — with a standard treatment. Low doses of statins were used (atorvastatin 10–20 mg/day or rosuvastatin 5–10 mg/day) in 213 patients (27.2%) and 89 patients (11.4%) received moderate or high doses of statins (atorvastatin 40–80 mg/day or rosuvastatin 20 mg/day) in combination with ursodeoxycholic acid (UDCA) preparations (750–1750 mg/day). Results. In the low-dose statin subgroup, the rate of low-density lipoprotein cholesterol levels reduction averaged 17.6 (5.6) % of the initial values; triglycerides, respectively, 12.3 (3.5) % of the initial values; that was statistically significantly lower than in the moderate/high dose statin plus UDCA subgroup of 32.9 (5.4) % and 18.7 (3.2) %, respectively, all p<0.001. In group 1, the average duration of hospital stay and the percentage of postoperative complications were statistically significantly lower in patients who received lipid-lowering therapy (28.5 (3.6) days and 8.8 (2.9) %), compared with those who did not receive this treatment (34.0 (2.8) days and 13.1 (2.6) %); p < 0.001. Similar differences in the length of hospital stay and the percentage of postoperative complications, depending on the lipid-lowering therapy, also occurred in groups 2, 3, and 4 (p < 0.001). Conclusions. The use of lipid-lowering therapy, including moderate / high doses of statins in combination with UDCA, contributed to a decrease in the length of hospital stay and a decrease in the incidence of postoperative complications in all groups of patients with DF.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79070130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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