A. R. Rosandy, Anis Asmi Azman, R. Khalid, Rizafizah Othaman, Mohamad Azwani Shah Mat Lazim, Iqbal M. Choudary, Yana M. Syah, Jalifah Latip, Ikram M. Said, Muntaz Abu Bakar
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引用次数: 0

摘要

在班廷丹戎塞巴特收集了巴豆的根,用于研究其化学成分。样品干燥后研磨,在室温下用甲醇溶剂提取3天,得到18.25克粗提取物。粗提物经薄层色谱(TLC)分析,真空柱层析(VLC)分馏,径向层析(RC)分离得到纯化化合物。通过核磁共振(NMR)、傅里叶变换红外(FT-IR)和质谱分析对所得化合物进行了结构鉴定,并鉴定为两个新化合物,分别命名为(-)-5,8-二羟基麻风phan-3-one(1)和(+)-14,16,17-三羟基kauran-1-on(2),总质量分别为4.9 mg和4.5 mg。这两个化合物在该属中首次报道。
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Diterpenoid-diterpenoid terbaharu daripada akar Croton hirtus (Euphorbiaceae)
The root of Croton hirtus was collected at Tanjung Sepat, Banting for study of its chemical compounds. This sample was dried before being ground and extracted using the methanol solvent at room temperature for three days yielding 18.25 gram of crude extract. The crude extracts obtained were analysed using thin layer chromatography (TLC) then fractionated via vacuum column chromatography (VLC) and proceed the isolation using radial chromatography (RC) to get the pure compounds. The pure compounds obtained were elucidated by nuclear magnetic resonance (NMR), Fourier Transform Infrared (FT-IR) and mass spectroscopy to confirm their structures and from that analysis, the compounds were identified as two new compounds naming (-)-5,8-dihydroxyjatrophan-3-one (1) and (+)-14,16,17-trihydroxykauran-1-on (2) with total weight 4.9 mg and 4.5 mg respectively. This two compound were reported for this time on this genus.
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