胰腺癌肿瘤微环境的研究进展

N. Pu, Guo-chao Zhao, Y. Lv, Wenchuan Wu
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引用次数: 2

摘要

胰腺癌是生物学上已知的高恶性肿瘤,缺乏有效的诊断和治疗方法。肿瘤微环境被普遍认为是肿瘤侵袭转移的重要促进因子。本文通过对胰腺癌肿瘤微环境中基质细胞、炎症和缺氧等方面的研究进展进行综述,旨在深入了解肿瘤进展机制,为胰腺癌的诊断和治疗提供有效依据。
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The advancement of tumor microenvironment in pancreatic carcinoma
Pancreatic cancer is the known kind of tumor biologically featured as high malignancy, lack of effective methods for diagnosis and treatment. Tumor microenvironment is generally considered as an important promotor in tumor invasion and metastasis. This review aims to deeply understand the mechanism of the tumor progression and validly provide the evidence for diagnosis and treatment by means focusing on the advances in the research of pancreatic cancer in the fields of stromal cells, inflammation and hypoxia in the tumor microenvironment of pancreatic carcinoma.
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