亚齐麻风患者概况:回顾性研究

Nanda Earlia, S. S. Budini, Dea Silvia Ramadana, Mikyal Bulqiah, Aqil Yuliawan Tasrif, Randika Richard R, Muhammad Adji Pangestu, Annisa Raihani, Auni Batrisyia, Eva Cahyaningsih, Fanny Adlin Nurafika, Istiqomah Genepo, Nadira Sabrina Mufti
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摘要

背景:麻风是一种由细胞内专性麻风分枝杆菌引起的慢性肉芽肿性传染病。麻风病在发病过程中可引起皮肤感觉丧失,伴有或不伴有病变,以及身体功能障碍。在亚齐,2019年有337例新的麻风病病例,这是苏门答腊最高的病例。目的:分析班达亚齐医院皮肤性病科麻风患者的情况。方法:采用回顾性设计的观察性描述性研究,使用2017年1月至2021年12月在班达亚齐皮肤病性病门诊RSUDZA就诊的麻风患者的病历。结果:本研究共获得麻风患者183例。大多数病例发生在男性患者(68.3%),大多数患者在18-40岁年龄组(60.1%),大多数患者居住在班达亚齐以外(71%)。最常见的麻风病报告类型是多菌型(71.6%)。无残疾麻风患者占35.5%,多数未发生麻风反应(71%),病变形态最常见为红斑(29.5%),细菌学和形态学指标阴性比例最高(分别为46.4%和50.8%)。结论:麻风病的诊断应以临床、细菌学和组织病理学为依据。早期诊断、患者获得治疗、早期开始治疗和坚持治疗将减少疾病传播,从而减少亚齐麻风病的流行。
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The Profile of Leprosy Patients in Aceh: Retrospective Study
Backgrounds: Morbus Hansen or leprosy is a chronic granulomatous infectious disease caused by the obligate intracellular Mycobacterium leprae bacillus. Leprosy can cause loss of sensation in the skin with or without lesions and body dysfunction during the course of the disease. In Aceh, there were 337 new cases of leprosy in 2019 and this was the highest case in Sumatra. Purpose: To analyze the profile of leprosy patients in the Department of Dermatology and Venereology of RSUDZA Banda Aceh. Methods: Observational descriptive study with retrospective design, using medical record of leprosy patients who visited Dermatology and Venereology Outpatient Clinic RSUDZA Banda Aceh for the period of January 2017 – December 2021. Result: A total of 183 leprosy patients were obtained from the study. Most cases occured in male patients (68.3%), the majority was in the 18-40 year age group (60.1%), most patients live outside of Banda Aceh (71%). The most frequently reported type of leprosy was the multibacillary type (71.6%). Leprosy patients without disability were 35.5%, the majority did not experience a leprosy reaction (71%), the most common morphology of the lesion was erythematous (29.5%), and the highest proportion of the bacteriological and morphological index was negative (46.4% and 50.8% respectively). Conclusion: The diagnosis of leprosy was based on clinical, bacteriological, and histopathological features. Early diagnosis, patient access to treatment, early initiation of treatment and adherence to therapy would reduce the disease transmission thus would decrease the prevalence of leprosy in Aceh.
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