儿童缺铁性贫血的超声及多普勒超声表现

M. Koç, F. Girgin, S. Serhatlioglu
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摘要

目的:缺铁性贫血(IDA)是世界范围内儿童的一个重要健康问题。它影响生长和智力运动的发展。在IDA的发展过程中,铁元素减少,导致缺铁(ID)。在文献中,没有关于超声(US)和多普勒超声在IDA发展中的发现的信息。本研究的目的是探讨铁含量减少、内源性贫血和缺铁症患儿的肝、脾及主要血管结构的超声及多普勒超声表现。材料和方法:本研究包括160例实验室结果为铁含量降低(n=43)、铁含量低(n=52)和铁含量低(n=65)的患者。对照组为50名儿童。测定肝脏和脾脏的实质回声大小、CCA Vmax -Vmin、ICA Vmax -Vmin及其脉搏(PI)和电阻指数(RI)。结果:肝肿大23例(35%),脾肿大8例(12%)合并IDA。CCA Vmax -Vmin、ICA Vmax -Vmin、CCA合并ICA的RI PI指数组间比较,差异均有统计学意义(p<0.05)。结论:IDA可见肝、脾肿大。贫血的增加会引起血管流速的改变,也会增加大脑的血容量。如果贫血在早期阶段被发现,并进行适当的治疗,儿童就不会出现认知障碍。在诊断中,超声和多普勒超声检查是有用的。
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Ultrasonography and Doppler ultrasonography findings of children with iron deficiency anemia
Aim: Iron deficiency anemia (IDA) is an important health problem in children in the worldwide. It affects both growth and mental motor development. Iron decrease then irons deficiency (ID) occurs during the developing of IDA. In the literature, there is no information about ultrasonography (US) and Doppler US findings in the development of IDA. The aim of this study is to search the US and Doppler US findings of liver, spleen and main vascular structures of children with the iron decrease, ID, and IDA. Material and Methods: This study including 160 patients who have the iron decrease (n=43), ID (n=52), and IDA (n=65) in laboratory findings. The control group was 50 children. The liver and spleen sizes with parenchymal echogenicity, CCA Vmax -Vmin, ICA Vmax -Vmin, their pulsatility (PI) and resistive index (RI) were measured. Results: 23 patients (35%) were diagnosed with hepatomegaly and 8 patients (12%) were diagnosed with splenomegaly having IDA. There was a statistically significant difference between the groups in terms of CCA Vmax -Vmin, ICA Vmax -Vmin, and also RI PI index of CCA with ICA (p<0.05). Conclusion: Hepatomegaly and splenomegaly can be seen in IDA. Increasing of anemia cause changes in the vascular flow velocities, and also increase the blood volume of the brain. If anemia is detected at an early stage and treatment is regulated, cognitive disturbances will not occur in children. In the diagnosis, an US and a Doppler US examination are useful.
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