非手术和手术牙周治疗降低糖尿病患者糖化血红蛋白的效果

Aspesi, López-Jarana, F. Salazar, AS Vinhas, M. Relvas
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引用次数: 1

摘要

糖尿病是一种全球性大流行疾病,是一种多种病因的代谢性疾病,其特征是由胰岛素分泌、胰岛素作用或两者兼而有之的缺陷引起的慢性高血糖。牙周炎是一种慢性炎症性疾病,由牙菌斑生物膜的积累引起,其中微生物生态失调导致慢性、非溶解性和破坏性炎症反应。在过去的几十年里,许多研究调查了牙周治疗对糖尿病患者血糖控制的影响。本文的目的是对已发表的文献进行回顾,以了解牙周治疗与糖化血红蛋白(HbA1c)值之间的关系。在PUBMED上进行了一次搜索,在277篇文章中,只有21篇被认为是更相关的。正如人们一段时间以来所认识到的那样,研究结果表明这两种疾病之间存在相关性,它们之间的联系在于炎症过程。在糖尿病患者中,这导致HbA1c值升高,并且难以控制。在血糖控制不佳的复杂临床情况下,通过口腔卫生协议和牙周治疗来控制牙周组织的炎症状态有几个好处。非手术牙周治疗可显著降低糖尿病患者的HbA1c水平。
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Effectiveness of Non-Surgical and Surgical Periodontal Therapy in Lowering HbA1c in Diabetic Patients
Diabetes is global pandemic disease, a metabolic disorder of multiple etiology that is characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Periodontitis is a chronic inflammatory disease that is initiated by the accumulation of dental plaque biofilm, within which microbial dysbiosis leads to a chronic, non-resolving and destructive inflammatory response. In the last decades, many studies investigated the impact of periodontal treatment on glycemic control in people with diabetes. The aim of this dissertation is to conduct a review of the published literature to understand the association between periodontal therapy and glycated hemoglobin (HbA1c) values. A search was conducted in PUBMED and of the 277 articles found, only 21 were considered for being more relevant. As has been recognized for some time, the results show a correlation between the two diseases and their link lies in the inflammatory process. In the diabetic patient, this results in higher HbA1c values and a situation that is difficult to control. Being able to control the inflammatory state of the periodontium through oral hygiene protocols and periodontal therapy has several benefits in a complicated clinical picture in situations of poor glycemic control. Non-surgical periodontal therapy proves effective in significantly lowering HbA1c levels in diabetic patients.
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