用皮肤点刺试验研究沙特阿拉伯吉达地区皮肤对各种过敏原的敏感性

Eman Beyari, Hussein A. Almehdar
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引用次数: 1

摘要

皮肤点刺试验是对变态反应性疾病较为重要的诊断试验之一,它采用不同变态反应原合成的变态反应性提取物。本研究对83例过敏者和20例对照者(男54例,女49例)进行皮肤点刺试验。这项试验是在阿卜杜勒阿齐兹国王大学医院的过敏诊所进行的,试验使用了从吉达市分离出来的9种不同的过敏原。使用的过敏原为2种屋尘螨提取物、屋尘提取物和6种鉴定真菌提取物。将提取液用于皮肤点刺试验,并与加拿大Omega公司进口的同种商业过敏原提取物进行比较。结果显示,两种结果之间存在显著差异,加拿大提取物优于沙特提取物。结论:与加拿大进口过敏原相比,沙特产过敏原的皮肤点刺试验是可以应用的,并给出了有价值的结果。此外,沙特的过敏原需要更多的研究来标准化,以产生有希望的经济影响结果。
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Studies on Skin Sensitivity to Various Allergens in Jeddah, Saudi Arabia Using Skin Prick Test
Skin prick test is one of the more important diagnostic tests against allergic diseases, it uses a synthesized allergic extracts from different allergens. In this study skin prick test was done on 83 allergic persons and 20 controls (54 male and 49 female). The test was done in the Allergic Clinic in the King Abdulaziz University Hospital with 9 different allergens which were isolated from Jeddah city. The used allergens were extract of 2 species of house dust mite, extract of house dust and extracts of 6 species of identified fungi. The extracts were used in the skin prick test and compared with the same commercial allergen extracts, imported from Omega company, Canada. The results revealed a significant difference between the two results and the Canadian extracts were better than the Saudi extracts. Conclusion: From the over mentioned results could concluded that the Saudi allergens able to be applied and gave the valuable results if compared with the imported Canadian allergens which isvery expensive using skin prick test. Also the Saudi allergens need more studies to standardize to give promising economic impact results.
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