一名肝硬化患者的COVID-19

Lia Sasmithae
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引用次数: 0

摘要

2019冠状病毒病大流行是一种新型疾病,对当前的医疗卫生体系提出了巨大挑战。COVID-19病毒对肝脏的确切影响尚不清楚。然而,在慢性肝病患者中,大多数COVID-19感染会影响生存率并引发肝脏失代偿。本研究报告了一名50岁的男性,他抱怨呕吐血和黑焦油便感染了COVID-19。体格检查发现:呕血、结膜苍白、腹水、侧静脉;从直肠触碰器上,发现了黑肠。没有发烧、咳嗽或呼吸急促。实验室及影像学检查示:常染性常胞性贫血,低白蛋白血症,ALT/AST、HBsAg(+)轻度升高,腹部超声示肝硬化伴腹水。筛查患者进行COVID-19抗原拭子试验(+),并进一步进行COVID-19 PCR拭子试验(+)。吐血黑黑的治疗方法为胃凉;禁食后滴注生长抑素PPI、注射维生素K、输注PRC、乳果糖、头孢曲松、腹水穿刺、白蛋白输注。出血消退后,给予螺内酯和心得安。COVID-19的治疗方法是阿奇霉素、Favivirapir、维生素D、维生素K和锌。患者住院11天后病情好转。结论:本研究报告了一例50岁男性肝硬化食管静脉曲张破裂并合并COVID-19感染的病例,尽管医院设施有限,但经综合治疗病情好转。
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COVID-19 in A Liver Cirrhosis Patient
The COVID-19 pandemic is a novel disease and posed a great challenge in the current healthcare system. The exact impact of the COVID-19 virus on the liver is still unknown. However, in a patient with chronic liver disease, most COVID-19 infections will affect the survival rate and initiate liver decompensation. This study reported a 50-years-old man who complained about bloody vomit and black tarry stool with COVID-19 infection. Physical examination findings included hematemesis, pale conjunctiva, ascites, collateral vein; and from the rectal toucher, there was melena. There was no fever, cough, or shortness of breath. The laboratory and radiological examinations showed that there were normochromic normocytic anemia, hypoalbuminemia, slightly increased ALT/AST, HBsAg (+), and abdominal ultrasound findings were liver cirrhosis with ascites. The patient was screened for the COVID-19 antigen swab test (+), further confirmed by the COVID-19 PCR swab test (+). The treatment given for hematemesis and melena was Gastric Cooling; the patient was fasted, then received somatostatin PPI drip, Vitamin K injection, PRC transfusion, lactulose, ceftriaxone, ascites fluid puncture, and albumin transfusion. After the bleeding resolved, the patient received spironolactone and propranolol. The treatments for COVID-19 were Azithromycin, Favivirapir, Vitamin D, Vitamin K, and Zinc. The patient was hospitalized for 11 days and then improved. Conclusion: This study reported a case of a 50 years-old man with ruptured esophageal varices due to liver cirrhosis with concomitant COVID-19 infection and improved with comprehensive therapy despite the limited facilities at the hospital.
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