恶性黑色素瘤病例预后因素评估

Betül Peker Cengiz, F. Tugrul
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摘要

简介:黑色素瘤是一种常见于皮肤的肿瘤,发病率高,死亡率逐年上升。反映这种在我国具有很高死亡率的肿瘤数据的研究今天仍然有限。我们的研究目的是回顾性评价我院治疗的皮肤黑色素瘤病例,并与其他研究进行比较。材料与方法:对2010 - 2019年我院病理门诊确诊为皮肤黑色素瘤的57例患者的临床及组织病理学特征进行分析。结果:患者平均年龄(1956年)63.18岁16.54岁。病变位于头颈部21例(36.8%),下肢16例(28.1%),上肢11例(19.3%),躯干9例(15.8%)。在我们的病例中,9例(15.8%)患者在至少1年和最多10年的随访期间发生转移。在本研究中,40例(70.2%)患者被诊断为结节性黑色素瘤,8例(14%)为浅表黑色素瘤,2例(3.5%)为lentigo, 7例(12.3%)为肢端黑色素瘤。讨论与结论:因此,我们的大多数黑色素瘤病例在头颈部因阳光照射而表现为结节型。我们的研究表明,这些患者在后期申请到卫生机构。在黑色素瘤中,早期诊断严重影响预后。
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Evaluation of Prognostic Factors in our Malignant Melanoma Cases
Introduction: Melanomas are neoplasms that usually develop on the skin with a high prevalence and a mortality rate that is increasing year by year. Studies reflecting the data of this neoplasm, which has a very high mortality rate in our country, are still limited today. Our aim in our study was to retrospectively evaluate the skin melanoma cases treated in our hospital and to compare them with other studies. Material and Method: The clinical and histopathological features of 57 patients diagnosed with skin melanoma in the pathology clinic of our hospital between 2010 and 2019 were examined. Results: The mean age (1956) of patients was 63.18  16.54 years. The lesions were located in the head and neck in 21 patients (36.8%), in the lower extremities in 16 patients (28.1%), in the upper extremities in 11 patients (19.3%) and in the trunk in 9 patients (15.8%). Metastasis developed in 9 (15.8%) patients during a minimum 1-year and maximum 10-year follow-up of our cases. In the present study, 40 patients (70.2%) were diagnosed with nodular melanoma, 8 (14%) with superficial melanoma, 2 (3.5%) with lentigo and 7 (12.3%) with acral melanoma. Discussion and Conclusion: As a result, most of our melanoma cases appeared as nodular type in the head and neck region due to sun exposure. Our study showed that these patients applied to the health institution in the late stage. In melanoma, early diagnosis seriously affects the prognosis.
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