海地人体免疫缺陷病毒检测中结核病主动病例发现的诊断率。

IF 0.5 Q4 MARINE & FRESHWATER BIOLOGY REVMAR-Revista Ciencias Marinas y Costeras Pub Date : 2019-11-01 DOI:10.5588/ijtld.18.0835
V R Rivera, L Lu, O Ocheretina, M A Jean Juste, P Julma, D Archange, C G Moise, F Homeus, P D Phanor, S Petión, P-Y Cremieux, D W Fitzgerald, J W Pape, S P Koenig
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引用次数: 0

摘要

设置:海地太子港的 Groupe Haïtien d'étude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO) 中心通过在人类免疫缺陷病毒(HIV)检测时筛查所有结核病(TB)患者来促进 "检测和治疗 "策略。目的:1)确定在 HIV 检测中被诊断为肺结核的慢性咳嗽患者的比例,并根据 HIV 检测结果进行分层;2)评估 Xpert® MTB/RIF 与痰显微镜检查相比的额外诊断率。设计:我们进行了一项回顾性队列分析,包括 2014 年 8 月至 2015 年 7 月在 GHESKIO 进行 HIV 检测的所有成人。1116名(38%)HIV阳性患者报告了持续≥2周的慢性咳嗽;984名(88%)接受了检测,265名(27%)被诊断为肺结核。5985(23%)名艾滋病毒阴性患者报告了慢性咳嗽;5654(94%)人接受了检测,1179(21%)人被诊断为肺结核。在所有细菌学确诊病例中,27%为涂片阴性和 Xpert 阳性。在所有肺结核病人中,81% 的人艾滋病毒呈阴性:结论:在 HIV 检测中筛查肺结核,无论是在 HIV 感染者中还是在 HIV 阴性者中都是高产的。应在 HIV 检测时对出现慢性咳嗽的患者进行这两种疾病的检测。
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Diagnostic yield of active case finding for tuberculosis at human immunodeficiency virus testing in Haiti.

SETTING: The Groupe Haïtien d'étude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO) Centres, Port-au-Prince, Haiti, facilitate "test and treat" strategies by screening all patients for tuberculosis (TB) at human immunodeficiency virus (HIV) testing.OBJECTIVE: 1) To determine the proportion of patients with chronic cough at HIV testing diagnosed with TB, stratified by HIV test results; and 2) to evaluate the additional diagnostic yield of Xpert® MTB/RIF vs. sputum microscopy.DESIGN: We conducted a retrospective cohort analysis including all adults tested for HIV at GHESKIO from August 2014 to July 2015.RESULTS: Of 29 233 adult patients tested for HIV, 2953 (10%) were diagnosed as HIV-positive. Chronic cough lasting ≥2 weeks was reported by 1116 (38%) HIV-positive patients; 984 (88%) were tested and 265 (27%) were diagnosed with TB. Chronic cough was reported by 5985 (23%) HIV-negative patients; 5654 (94%) were tested and 1179 (21%) were diagnosed with TB. Of all bacteriologically confirmed cases, 27% were smear-negative and Xpert-positive. Among all TB patients, 81% were HIV-negative.CONCLUSIONS: Screening for TB at HIV testing was high-yield, among both HIV-infected and HIV-negative individuals. Testing for both diseases should be conducted among patients who present with chronic cough at HIV testing.

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来源期刊
REVMAR-Revista Ciencias Marinas y Costeras
REVMAR-Revista Ciencias Marinas y Costeras MARINE & FRESHWATER BIOLOGY-
CiteScore
0.70
自引率
0.00%
发文量
3
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