焦虑与功能性便秘的关系:一项针对伊朗医学实习生的多中心研究

A. Yousefi, Babak Kardarian, Seyed Mojtaba Hashemi, S. Noorbakhsh
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摘要

背景:功能性便秘及其相关易感因素在医务人员中较为常见。研究目的:了解伊朗实习医师中功能性便秘的患病率及其与心理障碍的关系。方法:对2016-2017年在伊朗5所主要医学大学附属教育医院实习的369名医学实习生进行多中心横断面研究。提出与功能性便秘的ROME标准相关的问卷,以确认或拒绝疾病的明确诊断。为了评估参与者的抑郁、焦虑和压力状态,使用了先前由伊朗研究人员验证的波斯版das -21问卷。结果:总体而言,实习医师功能性便秘患病率为26.3%;且女性发病较多(p=0.043)。它与病例(p=0.1)或基线参数(婚姻状况、体重指数、抑郁严重程度或压力状态程度)无关。但与焦虑严重程度(p=0.004)和不规律吃早餐(p=0.041)有关;故意忽略排便(p=0.010)。结论:伊朗实习医生功能性便秘发生率高,尤其是女性,吃早餐率低,故意忽略排便,均可能提示焦虑在伊朗实习医生功能性便秘中的主要作用。因此,对功能性便秘患者进行心理咨询可能会有所帮助。
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The relation between anxiety and functional constipation: A multicenter study in Iranian medical interns
Background: Functional constipation and its-related predisposing factors are so frequent among medical staff. The aim of study: To determine the prevalence of functional constipation and its relation to psychological disorders among Iranian medical interns. Methods: This multicenter, cross-sectional study was performed on 369 medical interns working at 5 main educational hospitals affiliated by universities of medical sciences in Iran during 2016-2017. The questionnaires related to the ROME criteria definitive for functional constipation were raised to confirm or reject definitive diagnosis of disease. To assess depression, anxiety and stress status of the participants, it was used the Persian version of the DASS-21 questionnaire that was previously validated by the Iranian researchers. Results: Overall, the prevalence of functional constipation in medical interns was 26.3%; and was more frequent in female gender (p=0.043). It was not related to depression in cases (p=0.1) or baseline parameters (marital status, body mass index, severity of depression, or degree of stress status). But was related to severity of anxiety (p=0.004) and irregular eating breakfast (p=0.041); deliberately ignoring defecation (p=0.010). Conclusion: It can be concluded high prevalence of functional constipation in medical interns especially in female gender, cases with low rate of eating breakfast, and deliberately ignoring defecation all might indicate the major role for anxiety in functional constipation in Iranian medical interns. Thus, the psychologic consults programs for modifying the anxiety in cases with functional constipation might be helpful.
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