国产掺硅生物活性磷酸钙陶瓷的骨整合性能

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Polish Journal of Medical Physics and Engineering Pub Date : 2023-06-01 DOI:10.2478/pjmpe-2023-0013
V. Pidgaietskyi, N. Ulianchych, V. Kolomiiets, M. Rublenko, V. Andriiets'
{"title":"国产掺硅生物活性磷酸钙陶瓷的骨整合性能","authors":"V. Pidgaietskyi, N. Ulianchych, V. Kolomiiets, M. Rublenko, V. Andriiets'","doi":"10.2478/pjmpe-2023-0013","DOIUrl":null,"url":null,"abstract":"Abstract Introduction The relevance of this study lies in the fact, that today the search for biocompatible materials for the management of bone defects is of importance. Such materials could become an alternative to transplants. For the replacement of bone defects, two-phasic bioactive ceramics of hydroxyapatite and β-tricalcium phosphate is a very attractive biomaterial due to its excellent biocompatibility and osteoconductivity, but the results of its use are quite controversial due to insufficient bioactivity. The purpose of this work is to investigate the osseointegration properties of two-phase bioactive ceramics doped with silicon (HTdSi), both as a single component and a component in combination with platelet-rich fibrin, as well as in comparison with the well-known imported analogue – BIO, which consists of β-tricalcium phosphate, also as an independent component and a component in combination with platelet-rich fibrin. In the experiment, the rabbits of the New Zealand white breed at the age of 3 months and with an average weight of 2.5 kg were used. The terms of implantation are 30, 60, 90 and 180 days. The advantages of the domestic bio-composite are substantiated on the basis of clinical, radiological and histological studies. Material and methods In the experiment, the rabbits of the New Zealand white breed at the age of 3 months and with an average weight of 2.5 kg were used. The terms of implantation are 30, 60, 90 and 180 days. Results The osteointegration properties of two-phase bioactive ceramics doped with silicon (HTdSi), both as a single component and in combination with platelet fibrin, were investigated, as well as in comparison with the known imported analog - BIO, which contains β-tricalcium phosphate, both as a single component and in combination with platelet fibrin. Conclusions The advantages of domestic biocomposite are substantiated on the basis of clinical, radiological and histological studies.","PeriodicalId":53955,"journal":{"name":"Polish Journal of Medical Physics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Osseointegration properties of domestic bioactive calcium phosphate ceramics doped with silicon\",\"authors\":\"V. Pidgaietskyi, N. Ulianchych, V. Kolomiiets, M. Rublenko, V. Andriiets'\",\"doi\":\"10.2478/pjmpe-2023-0013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Introduction The relevance of this study lies in the fact, that today the search for biocompatible materials for the management of bone defects is of importance. Such materials could become an alternative to transplants. For the replacement of bone defects, two-phasic bioactive ceramics of hydroxyapatite and β-tricalcium phosphate is a very attractive biomaterial due to its excellent biocompatibility and osteoconductivity, but the results of its use are quite controversial due to insufficient bioactivity. The purpose of this work is to investigate the osseointegration properties of two-phase bioactive ceramics doped with silicon (HTdSi), both as a single component and a component in combination with platelet-rich fibrin, as well as in comparison with the well-known imported analogue – BIO, which consists of β-tricalcium phosphate, also as an independent component and a component in combination with platelet-rich fibrin. In the experiment, the rabbits of the New Zealand white breed at the age of 3 months and with an average weight of 2.5 kg were used. The terms of implantation are 30, 60, 90 and 180 days. The advantages of the domestic bio-composite are substantiated on the basis of clinical, radiological and histological studies. Material and methods In the experiment, the rabbits of the New Zealand white breed at the age of 3 months and with an average weight of 2.5 kg were used. The terms of implantation are 30, 60, 90 and 180 days. Results The osteointegration properties of two-phase bioactive ceramics doped with silicon (HTdSi), both as a single component and in combination with platelet fibrin, were investigated, as well as in comparison with the known imported analog - BIO, which contains β-tricalcium phosphate, both as a single component and in combination with platelet fibrin. Conclusions The advantages of domestic biocomposite are substantiated on the basis of clinical, radiological and histological studies.\",\"PeriodicalId\":53955,\"journal\":{\"name\":\"Polish Journal of Medical Physics and Engineering\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2023-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polish Journal of Medical Physics and Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2478/pjmpe-2023-0013\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish Journal of Medical Physics and Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/pjmpe-2023-0013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

摘要

本研究的相关性在于,今天寻找生物相容性材料用于骨缺损的治疗是非常重要的。这种材料可能成为移植的替代品。羟基磷灰石和β-磷酸三钙两相生物活性陶瓷由于其优异的生物相容性和骨导电性,是一种非常有吸引力的生物材料,但由于其生物活性不足,其使用结果颇有争议。本研究的目的是研究掺杂硅的两相生物活性陶瓷(HTdSi)作为单一组分和与富血小板纤维蛋白结合的组分的骨整合性能,并与众所周知的进口类似物- BIO进行比较,后者由β-磷酸三钙组成,也是作为独立组分和与富血小板纤维蛋白结合的组分。试验选用3月龄、平均体重2.5 kg的新西兰白兔。植入期为30天、60天、90天和180天。临床、放射学和组织学研究证实了国产生物复合材料的优势。材料与方法选用3月龄、平均体重2.5 kg的新西兰白兔。植入期为30天、60天、90天和180天。结果研究了硅掺杂两相生物活性陶瓷(HTdSi)单组份和与血小板纤维蛋白联合的骨整合性能,并与已知进口的β-磷酸三钙单组份和与血小板纤维蛋白联合的生物活性陶瓷- BIO进行了比较。结论国产生物复合材料的优势在临床、影像学和组织学研究的基础上得到证实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Osseointegration properties of domestic bioactive calcium phosphate ceramics doped with silicon
Abstract Introduction The relevance of this study lies in the fact, that today the search for biocompatible materials for the management of bone defects is of importance. Such materials could become an alternative to transplants. For the replacement of bone defects, two-phasic bioactive ceramics of hydroxyapatite and β-tricalcium phosphate is a very attractive biomaterial due to its excellent biocompatibility and osteoconductivity, but the results of its use are quite controversial due to insufficient bioactivity. The purpose of this work is to investigate the osseointegration properties of two-phase bioactive ceramics doped with silicon (HTdSi), both as a single component and a component in combination with platelet-rich fibrin, as well as in comparison with the well-known imported analogue – BIO, which consists of β-tricalcium phosphate, also as an independent component and a component in combination with platelet-rich fibrin. In the experiment, the rabbits of the New Zealand white breed at the age of 3 months and with an average weight of 2.5 kg were used. The terms of implantation are 30, 60, 90 and 180 days. The advantages of the domestic bio-composite are substantiated on the basis of clinical, radiological and histological studies. Material and methods In the experiment, the rabbits of the New Zealand white breed at the age of 3 months and with an average weight of 2.5 kg were used. The terms of implantation are 30, 60, 90 and 180 days. Results The osteointegration properties of two-phase bioactive ceramics doped with silicon (HTdSi), both as a single component and in combination with platelet fibrin, were investigated, as well as in comparison with the known imported analog - BIO, which contains β-tricalcium phosphate, both as a single component and in combination with platelet fibrin. Conclusions The advantages of domestic biocomposite are substantiated on the basis of clinical, radiological and histological studies.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Polish Journal of Medical Physics and Engineering
Polish Journal of Medical Physics and Engineering RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.30
自引率
0.00%
发文量
19
期刊介绍: Polish Journal of Medical Physics and Engineering (PJMPE) (Online ISSN: 1898-0309; Print ISSN: 1425-4689) is an official publication of the Polish Society of Medical Physics. It is a peer-reviewed, open access scientific journal with no publication fees. The issues are published quarterly online. The Journal publishes original contribution in medical physics and biomedical engineering.
期刊最新文献
Parametrization of subsegmental infarcts using high spatial resolution 2DSTE and synthetic ultrasonic data Automated differential diagnostics of respiratory diseases using an electronic stethoscope Evaluating the impact of anatomical changes on dose distributions in head and neck cancer Comparing eDQE and eNEQ metrics – is there an alternative approach to assessing image quality in digital mammography? Vascular stiffness in cold pressor test hyper-reactors
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1