一些取代咔唑N-Mannich碱的合成

Neetu Verma, Shruti Awasthi
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引用次数: 0

摘要

通过与多种仲胺和一系列醛(包括甲醛和乙醛)的反应,以咔唑为原料合成了新的咔唑衍生物缀合物。通过光谱研究确定了相应的类似物,并分别使用涡流热板法和最大电击诱发惊厥法测试了它们减轻疼痛和控制癫痫发作的能力。学生使用“t”检验创建统计分析,并将标准表示为平均SEM。
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Synthesis of N-Mannich Bases of some Substituted Carbazoles
Through reactions with numerous secondary amines and a series of aldehydes, including formaldehyde and acetaldehyde, novel carbazole derivative conjugates were created from carbazole. Corresponding analogues were identified through spectral studies, and they were tested for their ability to reduce pain and control seizures using the Eddy's Hot Plate method and the maximum electrical shock convinced convulsion method, respectively. Students created the statistical analysis using the "t" test, and the standards were stated as mean SEM.
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