尼帕病毒感染:尼泊尔为可能爆发的疫情做好准备了吗?

Dhiraj Shrestha, B. Bhattachan
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引用次数: 0

摘要

在世界上第一次尼帕病毒(NiV)爆发20年后,它再次出现在印度爆发。世卫组织已认识到NiV是对人类健康的一种强有力的流行病威胁。已记录了人畜共患NiV的动物-人传播和人-人传播。狐蝠科果蝠是该病毒的天然宿主。因此,这些蝙蝠的领土栖息地是NiV暴发的高风险区。症状是非特异性的,NiV的致病性尚不完全清楚。NiV感染的诊断仍然依赖于分子技术。到目前为止,还没有针对NiV的药物或疫苗被批准。一些研究提出了一系列可能的治疗和预防方案,但没有确定的注射意义。因此,适当的预防措施是目前唯一可用的预防措施。尼泊尔尚未爆发新冠肺炎疫情,但这并不影响对一般人群构成的风险。包括尼泊尔在内的高风险国家应做好充分准备,应对未来可能爆发的疫情。
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Nipah Virus (NiV) Infection: Is Nepal Prepared for the Possible Outbreak?
 After 20 years of the first Nipah Virus (NiV) outbreak in the world, it re-emerged as the outbreak in India. WHO has recognized NiV as a potent epidemic threat to human health. Both animal-to-human and human-to-human transmission of zoonotic NiV has been documented. Fruit bat of Pteropodidae family is the natural reservoir of the virus. Thus, the territorial habitat of these bats is the high risk zone of NiV outbreak. The symptoms are very nonspecific and the pathogenicity of NiV is yet to be fully understood. Diagnosis of NiV infection still relies on molecular techniques. Till date, no drugs or vaccines against NiV has been approved. Some research have presented arrays of the possible treatment and prevention option, but without sure shot implications. So, appropriate precautions are the only currently available prevention option. Nepal is yet to experience a NiV outbreak but that does not undermine the risk posed to the general population. High risk countries including Nepal should be well prepared to tackle the possible outbreak in future.
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