社区获得性肺炎抗生素处方趋势的系统评价

M. Zulkarnane A, K. Nair, Arul Mathivanan, K. Shirisha, Dr. S. Ramalakshmi
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引用次数: 0

摘要

社区获得性肺炎是世界上导致死亡的主要原因之一。本研究评估了社区获得性肺炎(CAP)管理中抗生素的处方趋势,并评估了抗生素培养敏感性模式。本研究强调合理使用抗生素,预防抗生素耐药,为未来患者保留抗生素。根据系统评价和荟萃分析首选报告项目(PRISMA)进行系统评价。研究者独立进行文献综述,筛选文章的相关性和合格性。最常见的革兰氏阳性微生物为肺炎链球菌,最常见的革兰氏阴性微生物为肺炎克雷伯菌。肺炎链球菌几乎对大环内酯类药物耐药。对研究患者最常见的双重治疗是β -内酰胺联合大环内酯类药物。该研究强调了正确选择抗生素以防止抗生素耐药性增加的重要性。
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Systematic review on prescribing trends of antibiotics in community acquired pneumonia
Community acquired pneumonia is one of the leading cause for death in the world. The study evaluates the prescribing trends of antibiotics in the management of community acquired pneumonia (CAP) and in assessing the antibiotic culture sensitivity pattern. The study highlights the usage of antibiotics rationally to prevent antibiotic resistance so that the antibiotic agents are preserved for future patients. A systematic review was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA). The investigators independently performed the literature review and screened the articles for relevance and eligibility. The most common gram positive microorganism was Streptococcus pneumoniae and the common gram negative microorganism was Klebsiella pneumoniae. Streptococcus pneumoniae is almost resistant to macrolides. The most common dual therapy prescribed to the study patients were beta-lactam combined with macrolides. The study emphasizes the importance of proper selection of antibiotics to prevent the increased incidence of antibiotic resistance.
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