糖尿病酮症酸中毒相关癫痫1例报告

Sakeena Kaukab Khan, A. Ayesha, Nagma Shireen, Ayesha Fatima, Sana Begum
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引用次数: 0

摘要

糖尿病酮症酸中毒是糖尿病的并发症,可由极度高血糖和酮症引起。这种情况在未经治疗的糖尿病患者或药物依从性患者中普遍存在。高血糖性高渗状态在临床上可表现为癫痫发作伴高血糖、无酮,发病率较低。患者男,55岁,表现为癫痫发作、吐白沫、咬舌、眼珠突出、呼吸短促、足部水肿、高血糖。既往病史包括10年来已知的高血压和糖尿病,定期使用胰岛素,不遵医嘱。经实验室检查,患者被诊断为继发于药物不依从性的高血糖糖尿病酮症酸中毒。患者采用胰岛素治疗方案-常规和基础胰岛素,抗生素,抗癫痫药物,每3小时持续监测血糖水平。糖尿病酮症酸中毒痊愈,术后无癫痫发作。提高对疾病状况、药物治疗和药物依从性的认识并对患者进行适当的教育,在控制病情以及防止在某些情况下可能致命的进一步并发症方面发挥着至关重要的作用。
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Diabetic ketoacidosis associated seizures: a case report
Diabetic ketoacidosis is the complicationof Diabetes mellitus, which can result due to extreme hyperglycemia and ketonaemia. This condition is prevalent among patients with untreated diabetes ordrug incompliance. Hyperglycemic hyperosmolar state can clinically be presented with episodes of seizures with high blood sugar levels and absence of ketones and has low incidence rate. A 55 year old male patient presented with episode of seizure, frothing, tongue bite, uprolling of eyes, shortness of breath, pedal edema and high blood sugar levels. Past medical history includes known hypertensive and diabetic since 10 years and is oninj regular insulin with non-adherence to medication. Lab investigations were performed and patient was diagnosed as hyperglycemic diabetic ketoacidosis secondary to drug incompliance. The patient was managed by insulin regimen- regular and basal insulin, antibiotics, antiepileptic drugs and by continuous monitoring of blood sugar levels every 3rd hourly. Diabetic ketoacidosis was recovered and later, there were no episodes of seizures. Creating awareness and proper patient education regarding the disease state, pharmacotherapy and drug compliance plays a vital role in managing the condition and as well as by preventing further complications that might be fatal in some cases.
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