镇痛剂的特性

Hadi Barru Hakam Fajar Siddiq, Dewi Rashati, Farida Suryaningsih
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引用次数: 0

摘要

N-(4t-丁基苯甲酰)-对氨基苯酚化合物是在H2SO4催化下由对氨基苯酚和4t-丁基苯甲酰氯合成的化合物。添加H2SO4催化剂的目的是加快化合物合成的反应速度,提高产品收率。N-(4t-丁基苯油)-对氨基酚化合物是一种有益的抗炎镇痛药。本研究拟采用H2SO4催化合成抗炎镇痛药N-(4t-丁基苯甲酰)-对氨基酚化合物,以确定其特性。本研究进行的表征包括物理表征和化学表征。物理表征为感官测试、晶型测试和熔点测试。化学性质采用紫外-可见分光光度法和红外光谱法。感官检测结果显示,样品呈粉末状,呈白灰色,无味道。N-(4t-丁基苯甲酰)-对氨基酚化合物熔点为193.33℃。紫外可见分光光度法的最佳波长为290nm和295nm。FTIR结果表明,N-(4t-丁基苯甲酰)-对氨基苯酚化合物有峰。关键词:N-(4 -丁基苯甲油)-对氨基苯酚;催化剂
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KARAKTERISASI SENYAWA ANALGETIKA-ANTIINFLAMASI N-(4t-BUTILBENZOIL)-p-AMINOFENOL YANG DISINTISES DENGAN KATALIS ASAM
The N-(4t-Butylbenzoyl)-p-Aminophenol compound was a synthesis compound between p-aminophenol and 4t-Butylbenzoyl chloride by using H2SO4 catalyst. The addition of H2SO4 catalyst purposed to accelerate the rate of rection in the synthesis of the compound and increased yield of product. The N-(4t-Butylbenzoil)-p-Aminophenol compound is beneficial as an antiinflammatory analgesic. This research were proposed to determine characteristics of the anti-inflammatory analgesic synthesis of N-(4t-Butylbenzoyl)-p-Aminophenol compound by using H2SO4 catalyst. Characterization conducted in this research were physical and chemical characterization. The physical characterization were organoleptic test, crystal form test and melting point test. While chemical characterization were UV-Vis spectrophotometry and FTIR. Result of organoleptic test showed sample had powder form, white-gray colour and not taste. Melting point of N-(4t-Butylbenzoyl)-p-Aminophenol compound was 193.33 °C. The optimum wavelength of UV-Vis spectrophotometry got 2 peaks at the wavelengths 290 and 295 nm. The result of FTIR showed that N-(4t-Butylbenzoyl)-p-Aminophenol compound had peaks.Keywords: N-(4t-butyl benzoil)-p-aminophenol, catalyst
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