{"title":"治疗乳腺癌的生物活性移植物共聚物","authors":"Manik Ghosh, R. Samanta, Harish Singh","doi":"10.3390/ecsoc-23-06512","DOIUrl":null,"url":null,"abstract":"Cancer is one of the most researched areas nowadays due to the increasing incidences of cancer patients and unavailability of cheap and highly efficient drugs. Cancer is the uncontrolled proliferation of the body’s own cell. The cancer cells are dedifferentiated and lose their normal function. Cancer may be of two types metastatic and benign, out of which metastatic cancer is serious form. We are aware of the fact that the cancer cells differ from normal cells in many aspects. One such aspect is pH of cancer cells. The cancer cell has a pH lower than that of the normal cells of the body. In this research, we have prepared target-specific and pH-sensitive bioactive polymer using a combination of different natural polymer like polyvinyl alcohol, sodium alginate in a different ratio. Since, these polymers are pH sensitive, they will release the loaded drug only at the cancer site thus reducing the various side effects of the drug and drug toxicity.","PeriodicalId":20537,"journal":{"name":"Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry","volume":"54 3 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"BIOACTIVE GRAFT CO-POLYMER FOR THE TREATMENT OF BREAST CANCER\",\"authors\":\"Manik Ghosh, R. Samanta, Harish Singh\",\"doi\":\"10.3390/ecsoc-23-06512\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cancer is one of the most researched areas nowadays due to the increasing incidences of cancer patients and unavailability of cheap and highly efficient drugs. Cancer is the uncontrolled proliferation of the body’s own cell. The cancer cells are dedifferentiated and lose their normal function. Cancer may be of two types metastatic and benign, out of which metastatic cancer is serious form. We are aware of the fact that the cancer cells differ from normal cells in many aspects. One such aspect is pH of cancer cells. The cancer cell has a pH lower than that of the normal cells of the body. In this research, we have prepared target-specific and pH-sensitive bioactive polymer using a combination of different natural polymer like polyvinyl alcohol, sodium alginate in a different ratio. Since, these polymers are pH sensitive, they will release the loaded drug only at the cancer site thus reducing the various side effects of the drug and drug toxicity.\",\"PeriodicalId\":20537,\"journal\":{\"name\":\"Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry\",\"volume\":\"54 3 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/ecsoc-23-06512\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/ecsoc-23-06512","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
BIOACTIVE GRAFT CO-POLYMER FOR THE TREATMENT OF BREAST CANCER
Cancer is one of the most researched areas nowadays due to the increasing incidences of cancer patients and unavailability of cheap and highly efficient drugs. Cancer is the uncontrolled proliferation of the body’s own cell. The cancer cells are dedifferentiated and lose their normal function. Cancer may be of two types metastatic and benign, out of which metastatic cancer is serious form. We are aware of the fact that the cancer cells differ from normal cells in many aspects. One such aspect is pH of cancer cells. The cancer cell has a pH lower than that of the normal cells of the body. In this research, we have prepared target-specific and pH-sensitive bioactive polymer using a combination of different natural polymer like polyvinyl alcohol, sodium alginate in a different ratio. Since, these polymers are pH sensitive, they will release the loaded drug only at the cancer site thus reducing the various side effects of the drug and drug toxicity.