银芹提取物抗氧化性能评价及纳米混悬液的制备

D. Chaudhari, A. Kharat
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摘要

众所周知,植物在健康中起着重要作用,并经常用于食品和医药工业,这是一个不争的事实。在植物部分中,叶、茎、根和树皮因其生物学特性而被广泛研究。然而,花卉总体上被忽视了,重要的活动没有被探索。凤仙花,苋科,古药用途广泛,历史悠久。从该植物中提取并鉴定了79多种化学物质,主要是皂苷、多肽、酚类、脂肪酸和氨基酸。皂苷被认为是草药的独特和有效成分。实验数据表明,这种草药中的有效成分具有广泛的生物效应,包括治疗多种眼病的能力。以甲醇和水为溶剂,对凤仙花进行了提取。通过化学试验对提取物进行了初步的植物化学分析。采用DPPH和H2O2技术对其抗氧化活性进行了评价。采用纳米沉淀法制备了银芹的纳米混悬液。银芹纳米混悬液增强了其抗氧化潜能和生物利用度。
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Evaluation of Antioxidant Potential and Formulation of Nanosuspension of Celosia argentea Extract
It is a well-known undisputed truth that plants play a significant role in health and are frequently used in the food and medicinal industries. Among plant parts, leaves, stems, roots, and bark are being extensively researched for their biological characteristics. However, flowers are overall neglected and significant activities were not explored. Celosia argentea, Family: Amaranthaceae is wide used as ancient drugs with long history. More than 79 chemicals, mostly saponins, peptides, phenols, fatty acids, and amino acids, were extracted and identified from this plant. Saponins are considered to be the distinctive and active components of the herb. Experimental data showed that the active ingredients in this herb have broad biological effects, including the ability to treat number of eye conditions. The flowers of Celosia argentea were collected and extracted using methyl alcohol and water as solvent. Preliminary phytochemical analysis of extracts were carried out by chemical tests. Antioxidant activity was evaluated for the hydroalcoholic extract by DPPH and H2O2 technique. Formulation of nanosuspension of Celosia argentea was carried out by Nanoprecipitation technique. Nanosuspensions of Celosia argentea potentiates the antioxidant potential and bioavailability.
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