菝葜的研究结果。正常高尿酸血症大鼠和高尿酸大鼠

Pharmacological research communications Pub Date : 1988-12-01 DOI:10.1016/S0031-6989(88)80841-5

D. Giachetti, I. Taddei, E. Taddei

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引用次数: 2

摘要

菝葜。在正常大鼠或经氧酸钾(250 mg/ kg)或果糖(4 g/kg)预处理的高尿酸血症和高尿酸血症大鼠中，以1或2 g/kg的剂量给药，在正常大鼠和经果糖预处理的大鼠中，不改变利尿作用，但增加尿酸和尿囊素的排泄，而在氧酸预处理的大鼠中则无活性。尿囊素血症不会被果糖或氧酸酯修饰，而尿酸血症则会被修饰。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Results of Smilax macrophylla Vers. in normal hyperuricemic and hyperuricosuric rats

Smilax macrophylla Vers., administred per os at the doses of 1 or 2 g/kg in normal rats or in rats made hyperuricemic and hyperuricosuric by potassium oxonate (250 mg/Kg p.o.) or fructose (4 g/Kg p.o.) does not modify diuresis, but increases the excretion of uric acid and allantoin in normal rats and in those pretreated with fructose, whereas it is inactive in oxonate pretreated rats. Allantoinemia is not modified by fructose or oxonate, whereas uricemia is modified.

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Pharmacological research communications

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