子宫内膜异位症对体外受精结果的影响

M. Herzog, Katarina Pavšlar, A. Vogler
{"title":"子宫内膜异位症对体外受精结果的影响","authors":"M. Herzog, Katarina Pavšlar, A. Vogler","doi":"10.6016/857","DOIUrl":null,"url":null,"abstract":"Introduction: Nowadays, endometriosis represents the most frequent cause of female infertility.The treatment of choice is by all means laparoscopic surgery, which results in more than a 60 % pregnancy rate, regardless of the stage of the disease. For the rest of patients in vitro fertilization (IVF) is the most appropriate treatment of choice. Views of the impact of endometriosis on IVF outcome remain controversial and subject to debate. Whereas some studies have documented that endometriosis is associated with reduced pregnancy rates, others failed to prove this association. The present study was designed to elucidate whether or not endometriosis affects IVF outcome at our institution. The study was retrospective, statistical significance was considered at p ≤ 0.05.\nMethods: In 96 patients (group A) that underwent IVF program the only cause of infertility was endometriosis which had been previously treated surgically. Sixty-two (64.6 %) patients had minimal or mild endometriosis (group C) and 34 (35.4 %) had moderate or severe stage of the disease (group D). The control group (group B) consisted of 305 patients who underwent IVF procedure for tubal or idiopathic infertility. Among other variables, pregnancy rate per cycle and per embryo transfer (ET), take-home-baby rate (THBR) per cycle and per ET were compared between the study and control groups of patients as well as between both groups with endometriosis. The study was retrospective. Statistical significance was defined as p ≤ 0.05.\nResults: No statistically significant differences were found in any of the compared parameters. In Group “A” pregnancy rate per cycle and per ET was 41.7 % and 46.8 % respectively, compared to Group “B” where it was 36.4 % and 40.5 % respectively. THBR per cycle and per ET in Group “A” was 35.4 % and 43.0 %, whereas in the control group it was 30.5 % and 33.9 % respectively. Pregnancy rate per cycle and per ET in Group “C” was 40.3 % and 48.1 % whereas in Group “D” it was 44.1 % and 55.6 % respectively. THBR per cycle and per ET in Group “C” was 33.9 % and 40.4 % whereas in Group “D” it was 38.2 % and 48.1 % respectively. \nConclusions: Endometriosis does not affect the outcome of IVF procedures. We believe that appropriate surgical technique is of paramount importance in patients with endometriosis, leading to favourable IVF outcomes.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"45 1","pages":"453-460"},"PeriodicalIF":0.0000,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"The impact of endometriosis on in vitro fertilization outcome\",\"authors\":\"M. Herzog, Katarina Pavšlar, A. Vogler\",\"doi\":\"10.6016/857\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Nowadays, endometriosis represents the most frequent cause of female infertility.The treatment of choice is by all means laparoscopic surgery, which results in more than a 60 % pregnancy rate, regardless of the stage of the disease. For the rest of patients in vitro fertilization (IVF) is the most appropriate treatment of choice. Views of the impact of endometriosis on IVF outcome remain controversial and subject to debate. Whereas some studies have documented that endometriosis is associated with reduced pregnancy rates, others failed to prove this association. The present study was designed to elucidate whether or not endometriosis affects IVF outcome at our institution. The study was retrospective, statistical significance was considered at p ≤ 0.05.\\nMethods: In 96 patients (group A) that underwent IVF program the only cause of infertility was endometriosis which had been previously treated surgically. Sixty-two (64.6 %) patients had minimal or mild endometriosis (group C) and 34 (35.4 %) had moderate or severe stage of the disease (group D). The control group (group B) consisted of 305 patients who underwent IVF procedure for tubal or idiopathic infertility. Among other variables, pregnancy rate per cycle and per embryo transfer (ET), take-home-baby rate (THBR) per cycle and per ET were compared between the study and control groups of patients as well as between both groups with endometriosis. The study was retrospective. Statistical significance was defined as p ≤ 0.05.\\nResults: No statistically significant differences were found in any of the compared parameters. In Group “A” pregnancy rate per cycle and per ET was 41.7 % and 46.8 % respectively, compared to Group “B” where it was 36.4 % and 40.5 % respectively. THBR per cycle and per ET in Group “A” was 35.4 % and 43.0 %, whereas in the control group it was 30.5 % and 33.9 % respectively. Pregnancy rate per cycle and per ET in Group “C” was 40.3 % and 48.1 % whereas in Group “D” it was 44.1 % and 55.6 % respectively. THBR per cycle and per ET in Group “C” was 33.9 % and 40.4 % whereas in Group “D” it was 38.2 % and 48.1 % respectively. \\nConclusions: Endometriosis does not affect the outcome of IVF procedures. We believe that appropriate surgical technique is of paramount importance in patients with endometriosis, leading to favourable IVF outcomes.\",\"PeriodicalId\":49350,\"journal\":{\"name\":\"Zdravniski Vestnik-Slovenian Medical Journal\",\"volume\":\"45 1\",\"pages\":\"453-460\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zdravniski Vestnik-Slovenian Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6016/857\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zdravniski Vestnik-Slovenian Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6016/857","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 1

摘要

简介:如今,子宫内膜异位症是女性不孕的最常见原因。治疗的选择是通过腹腔镜手术,结果超过60%的怀孕率,无论疾病的阶段。对于其余患者,体外受精(IVF)是最合适的治疗选择。子宫内膜异位症对体外受精结果的影响仍然存在争议。虽然一些研究证明子宫内膜异位症与妊娠率降低有关,但其他研究未能证明这种联系。本研究旨在阐明子宫内膜异位症是否会影响我们机构的体外受精结果。本研究为回顾性研究,p≤0.05认为有统计学意义。方法:96例(A组)经体外受精治疗的不孕不育的唯一原因是子宫内膜异位症。62例(64.6%)患者有轻微或轻度子宫内膜异位症(C组),34例(35.4%)患者有中度或重度子宫内膜异位症(D组)。对照组(B组)包括305例因输卵管性或特发性不孕症接受体外受精手术的患者。在其他变量中,研究人员比较了研究组和对照组之间以及子宫内膜异位症患者两组之间的每个周期和每个胚胎移植(ET)的妊娠率,每个周期和每个ET的带回家婴儿率(THBR)。该研究是回顾性的。统计学意义定义为p≤0.05。结果:各参数比较无统计学差异。A组每个周期和每个ET的妊娠率分别为41.7%和46.8%,而B组的妊娠率分别为36.4%和40.5%。A组每周期THBR和每ET分别为35.4%和43.0%,对照组分别为30.5%和33.9%。C组每周期妊娠率和每ET妊娠率分别为40.3%和48.1%,D组分别为44.1%和55.6%。C组每周期THBR和每ET分别为33.9%和40.4%,D组分别为38.2%和48.1%。结论:子宫内膜异位症不影响体外受精手术的结果。我们相信适当的手术技术对子宫内膜异位症患者至关重要,从而获得良好的体外受精结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The impact of endometriosis on in vitro fertilization outcome
Introduction: Nowadays, endometriosis represents the most frequent cause of female infertility.The treatment of choice is by all means laparoscopic surgery, which results in more than a 60 % pregnancy rate, regardless of the stage of the disease. For the rest of patients in vitro fertilization (IVF) is the most appropriate treatment of choice. Views of the impact of endometriosis on IVF outcome remain controversial and subject to debate. Whereas some studies have documented that endometriosis is associated with reduced pregnancy rates, others failed to prove this association. The present study was designed to elucidate whether or not endometriosis affects IVF outcome at our institution. The study was retrospective, statistical significance was considered at p ≤ 0.05. Methods: In 96 patients (group A) that underwent IVF program the only cause of infertility was endometriosis which had been previously treated surgically. Sixty-two (64.6 %) patients had minimal or mild endometriosis (group C) and 34 (35.4 %) had moderate or severe stage of the disease (group D). The control group (group B) consisted of 305 patients who underwent IVF procedure for tubal or idiopathic infertility. Among other variables, pregnancy rate per cycle and per embryo transfer (ET), take-home-baby rate (THBR) per cycle and per ET were compared between the study and control groups of patients as well as between both groups with endometriosis. The study was retrospective. Statistical significance was defined as p ≤ 0.05. Results: No statistically significant differences were found in any of the compared parameters. In Group “A” pregnancy rate per cycle and per ET was 41.7 % and 46.8 % respectively, compared to Group “B” where it was 36.4 % and 40.5 % respectively. THBR per cycle and per ET in Group “A” was 35.4 % and 43.0 %, whereas in the control group it was 30.5 % and 33.9 % respectively. Pregnancy rate per cycle and per ET in Group “C” was 40.3 % and 48.1 % whereas in Group “D” it was 44.1 % and 55.6 % respectively. THBR per cycle and per ET in Group “C” was 33.9 % and 40.4 % whereas in Group “D” it was 38.2 % and 48.1 % respectively. Conclusions: Endometriosis does not affect the outcome of IVF procedures. We believe that appropriate surgical technique is of paramount importance in patients with endometriosis, leading to favourable IVF outcomes.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
0.30
自引率
0.00%
发文量
65
审稿时长
4-8 weeks
期刊最新文献
The efficacy of an aerosol box to prevent infections during aerosol-generating procedures Sialendoscopy before, during and after the COVID-19 pandemic THE EFFECT OF SARTANS ON THE PREGNANCY PARAVAGINAL AND RETROPERITONEAL HAEMATOMA POST PARTUM Iatrogenic streptococcus salivarius meningitis: a case report
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1