特发性常压脑积水分流器类型对患者临床预后的影响

M. Akyol, E. Çetin
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摘要

背景:特发性常压脑积水(iNPH)是一种手术可逆的成人神经系统疾病。它是一种神经系统疾病,其特征是颅成像检测到脑室增大,以及步态障碍,认知能力下降和尿失禁,没有其他原因可以解释临床表现。脑室分流,主要是脑室-腹膜(VP)分流,已被证明是成功的缓解症状的患者。在这项研究中,我们的目的是探讨在我们诊所治疗的iNPH患者中使用的两种VP分流器的效果。方法:通过Enlyl系统对28例因静脉内ph引起的VP分流患者的临床和实验室记录进行回顾性分析。9例(32.1%)置入可编程分流器,19例(67.9%)置入中压分流器。结果:两种分流术在患者年龄、性别、术前检查等方面差异无统计学意义(p>0.05)。然而,与中压分流器组相比,可编程分流器组的共济失调步态发生率显著高于中压分流器组(p0.05)。结论:在本研究中,两种分流器的临床结果没有明显差异,因此两种分流器都是可行的选择。
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Effects Of Shunt Types Used In Idiopathic Normal Pressure Hydrocephalus On Patients' Clinical Outcomes
Background: Idiopathic normal pressure hydrocephalus (iNPH) is a surgically reversible neurological disorder in adults. It is a neurological condition characterized by ventricular enlargement detected on cranial imaging as well as gait disturbance, cognitive decline and urinary incontinence, with no other reason to explain the clinical findings. Ventricular shunting, predominantly ventriculoperitoneal (VP) shunt, has been shown to be successful in relieving symptoms in patients. In this study, we aimed to investigate the effects of two VP shunts used in the iNPH patients treated in our clinic. Methods: Clinical and laboratory records of 28 patients who underwent VP shunting due to iNPH were reviewed retrospectively via the Enlyl system. A programmable shunt was inserted in 9 (32.1%) and a medium-pressure shunt was inserted in 19 (67.9%) patients. Results: There was no significant difference between the two shunt types with regard to patient age, gender, and preoperative tests (p>0.05). However, the prevalence of ataxic gait was significantly higher in the Programmable Shunt group compared to the Medium-Pressure Shunt group (p<0.05). On the other hand, no significant difference was found between the shunt types with regard to postoperative examination findings and additional neurological disorders (p>0.05 for both). Conclusion: In the present study, no significant difference was observed between the shunt types with regard to clinical outcomes and thus both types of shunts were revealed as viable options.
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