三叉神经电刺激立体嗅觉

Jas Brooks, Shan-Yuan Teng, Jingxuan Wen, Romain Nith, Jun Nishida, Pedro Lopes
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引用次数: 27

摘要

我们提出了一种新型的嗅觉设备,通过电刺激用户的鼻中隔,将外部气味传感器的读数呈现为三叉神经感觉,从而产生立体气味体验,即关于气味位置的定向信息。关键是来自三叉神经的感觉,来自鼻子的神经末梢,在感知上与嗅球(大脑中感知气味的区域)的感觉融合在一起。因此,我们提出电刺激三叉神经是立体嗅觉增强/替代的理想选择,与其他方法不同,它不需要在嗅球中植入电极。为了实现这一点,我们设计了一个独立的设备,用户可以穿过他们的鼻中隔佩戴。我们的设备通过使用可变脉宽的电脉冲刺激用户的三叉神经来输出;它通过一个光反射器来感应使用者的吸入。它的尺寸为10x23毫米,并使用蓝牙与外部气体传感器通信。在我们的用户研究中,我们发现了关键的电波形参数,使用户能够感受到气味的强度(绝对电荷)和方向(相序和净电荷)。在我们的第二项研究中,我们证明了参与者能够通过使用我们的原型来定位房间中的虚拟气味源,而无需任何先前的培训。利用这些见解,我们的设备可以实现表达三叉神经的感觉,并可以作为嗅觉缺失症患者的辅助设备。
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Stereo-Smell via Electrical Trigeminal Stimulation
We propose a novel type of olfactory device that creates a stereo-smell experience, i.e., directional information about the location of an odor, by rendering the readings of external odor sensors as trigeminal sensations using electrical stimulation of the user's nasal septum. The key is that the sensations from the trigeminal nerve, which arise from nerve-endings in the nose, are perceptually fused with those of the olfactory bulb (the brain region that senses smells). As such, we propose that electrically stimulating the trigeminal nerve is an ideal candidate for stereo-smell augmentation/substitution that, unlike other approaches, does not require implanted electrodes in the olfactory bulb. To realize this, we engineered a self-contained device that users wear across their nasal septum. Our device outputs by stimulating the user's trigeminal nerve using electrical impulses with variable pulse-widths; and it inputs by sensing the user's inhalations using a photoreflector. It measures 10x23 mm and communicates with external gas sensors using Bluetooth. In our user study, we found the key electrical waveform parameters that enable users to feel an odor's intensity (absolute electric charge) and direction (phase order and net charge). In our second study, we demonstrated that participants were able to localize a virtual smell source in the room by using our prototype without any previous training. Using these insights, our device enables expressive trigeminal sensations and could function as an assistive device for people with anosmia, who are unable to smell.
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