海洋甲壳类合成银纳米粒子的有益生物应用

D. Beltagy, N. Abdo, N. Samak, Gihan M. El-khodary, K. Abdel-Aziz, M. Mona
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摘要

纳米银具有广泛的应用前景。AgNPs的生产可以通过不同的方法发生,化学,物理和绿色方法。最常用的方法是化学方法。海洋生物表现出广泛的生物活性。本研究旨在建立海洋甲壳类动物提取液的生物合成纳米银的方法。采用x射线衍射(XRD)、扫描电镜(SEM)和紫外可见光谱(UV-visible spectroscopy)对纳米颗粒的微观结构、形貌和光学吸收性能进行了表征。紫外可见吸收证实了银纳米粒子的形成,光谱在441.79 ~ 462.74 nm之间。XRD结果表明,所制备的纳米颗粒具有结晶性质。SEM图像检测到AgNPs的准球形形态。以马尾松雄鱼硬部海洋甲壳类提取液(HM4)制备的银纳米粒子在形态和粒径上效果最好。评价AgNPs (HM4)对不同肿瘤细胞系的抗病毒、抗微生物、抗糖尿病、抗关节炎、抗衰老和抗炎作用。AgNPs的表征在医学方面具有广阔的应用前景。
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Beneficial Bioapplications of Silver Nanoparticles Synthesized by a Marine Crustacean (Erugosquilla massavensis)
Silver nanoparticles (AgNPs) have wide applications. Production of AgNPs can be occurred through different method chemical, physical, and green methods. The most popular methods are chemical approaches. Marine organisms exhibit a wide range of bioactivity. The present study was designed to establish the biosynthesis of silver nanoparticles from marine crustacean extract of the hard and soft parts of male and female E. massavensis. The microstructure, morphology and optical absorption properties of the nanoparticles were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and UV-visible spectroscopy. The formation of silver nanoparticles was confirmed by Uv-Vis absorption and the spectra were observed plasmon bands between 441.79–462.74 nm. XRD results show that the nanoparticles are crystalline in nature. SEM images detected the quasi-spherical AgNPs morphological shape. Silver nanoparticles from marine crustacean extract of the hard part of male E. massavensis (HM4) showed the best results in morphology and particle size. Evaluation of the cytotoxicity of AgNPs (HM4) on different cancer cell lines antiviral, anti-microbial, anti-diabetic, anti-arthritic, anti-aging and anti-inflammatory properties were assessed. AgNPs characterization may be introduced a promising applications in medical aspects.
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