早期新生儿皮肤病:来自拉贾斯坦邦西部三级保健中心的流行病学研究

P. Choudhary, R. Mehta, Kamaldeep Singh, Vikas Mahla, B. Ghiya, Divyansha Sharma, Ashok Dhanwal
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摘要

背景:新生儿时期的皮肤表现从短暂的自限性到严重的危及生命的症状不等。应将暂时性和病理性新生儿皮肤病与生理性变化区分开来,避免不必要的治疗,减轻家长的压力。目的:本研究的目的是确定早期新生儿各种皮肤病的发病率和模式,并将这些变化与母体或新生儿因素联系起来;位于印度拉贾斯坦邦西部地区。方法:本前瞻性研究在一家三级转诊教学医疗中心进行,记录了5000名有任何生理和/或病理皮肤变化的早期新生儿的详细皮肤病学检查。结果:共观察新生儿5000例,其中男性3248例(64.96%),女性1752例(35.04%)。其中足月新生儿占67.36%,早产儿占30.44%,早产儿占2.2%。生理性皮肤改变(92.42%)较病理性皮肤改变(45.1%)更为常见。生理性皮肤变化发生率依次为皮脂腺增生(65.32%)、粟疹(51.12%)、生理性结垢(41.02%)。体重<2.5 kg的早产儿多见斑疹(2.06%)和丑角样皮肤变化(1.06%)。由于我们所在的湿热环境,39%的新生儿出现了粟疹。大疱性脓疱疮是199例新生儿中最常见的感染。最常见的医源性并发症是头部继位;在160个新生儿中发现。结论:新生儿皮肤病多为一过性生理性皮肤病,但应与严重侵袭性病理性皮肤病鉴别,避免不必要的治疗。
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Early neonatal dermatoses: An epidemiological study from a tertiary care center in Western Rajasthan
Background: The spectrum of cutaneous manifestations during the neonatal period varies from transient self-limiting conditions to serious life-threatening ones. Transient and pathological neonatal dermatoses should be differentiated from physiological changes to avoid unnecessary treatment and to relieve parent's stress. Purpose: The aim of this study was to determine the incidence and patterns of various dermatoses in early neonates and correlate these changes with maternal or neonatal factors; in the west region of Rajasthan, India. Methods: This hospital-based prospective study at a tertiary-level referral teaching medical center entailed recording detailed dermatological examination of 5000 early neonates having any physiological and/or pathological cutaneous changes. Results: A total of 5000 newborns were observed, there were 3248 (64.96%) male and 1752 (35.04%) female. Out of the total, 67.36% were full-term birth, whereas 30.44% were preterm and 2.2% were postterm newborns. Physiological skin changes (92.42%) were more commonly observed as compared to pathological changes (45.1%). The physiological skin changes observed in the order of frequency were sebaceous hyperplasia (65.32%), milia (51.12%), and physiological scaling (41.02%). Cutis marmorata (2.06%) and harlequin skin changes (1.06%) were seen more in preterms, weighing <2.5 kg. Miliaria was observed in 39% of neonates, due to the hot and humid environment at our place. Bullous impetigo was the most common infection observed in 199 neonates. The most common iatrogenic complication was caput succedaneum; noted in 160 neonates. Conclusion: Neonatal dermatoses are mostly transient and physiological, but these innocent dermatoses need to be differentiated from serious and aggressive pathological dermatoses to avoid unnecessary therapy.
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