三级医院糖尿病患者心血管风险概况的评估

Ganesh Anjani Sharma, S. Bala, Arun Guddeti, S. Katkuri, Suneeth Jogi, Jahnavi Dharmana
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引用次数: 0

摘要

背景:2型糖尿病与心血管疾病发病率和死亡率的关系是众所周知的事实。糖尿病患者中相关危险因素的测量为进一步管理和预防并发症提供了更好的想法,特别是在高危人群中。本研究的目的是比较糖尿病患者的心血管风险概况,并根据世界卫生组织(WHO)的风险图表估计糖尿病患者的10年心血管风险。方法以医院为基础的横断面研究,采用基于who逐步监测问卷的半结构化问卷,包括社会人口学变量、个人习惯和生活方式(物理和生化测量)。超声检查颈动脉内膜-中膜厚度(CIMT)。使用世界卫生组织/国际高血压学会(ISH)图表进行十年心血管疾病(CVD)风险评估。结果共纳入男性113例,女性144例。在心血管危险因素的比较中,男性和女性在吸烟和饮酒、收缩压(BP)、舒张压和高密度脂蛋白(HDL)方面存在统计学上的显著差异。CIMT测量结果显示了统计学上的显著差异,男性的风险明显更高。一项为期10年的心血管疾病风险评估显示,男性患心血管疾病的风险更高,且具有统计学意义。发现10年CVD风险增加与HbA1c、HDL、收缩压、舒张压和CIMT存在显著关联。结论糖尿病患者的性别间比较显示,根据WHO/ISH图表进行的10年风险评估,男性的心血管危险因素在统计学上更高。
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Estimation of Cardiovascular Risk Profile among Diabetic Patients Attending Tertiary Care Hospital
Background Association of type-2 diabetes mellitus with cardiovascular morbidity and mortality is a well-known fact. The measurement of associated risk factors among diabetics gives a better idea for further management and prevention of complications, especially among those with high risk. Objectives The objective of our study was to compare the cardiovascular risk profile and estimate the 10-year cardiovascular risk using the World Health Organization (WHO) risk chart among diabetic patients as per their gender. Methods Hospital-based cross-sectional study was undertaken among type 2 diabetic patients attending our tertiary care hospital using a semi-structured questionnaire based on WHO-STEPwise approach to surveillance questionnaire consisting of socio-demographic variables, personal habits, and lifestyle (physical and biochemical measurements). Carotid intima–media thickness (CIMT) was assessed through ultrasonography. Ten-year cardiovascular disease (CVD) risk assessment was also done using WHO/International Society of Hypertension (ISH) charts. Results One hundred and thirteen male and 144 female subjects were included in the study. On comparison of cardiovascular risk factors, a statistically significant difference among males and females was found in tobacco and alcohol consumption, systolic blood pressure (BP), diastolic BP, and high-density lipoprotein (HDL). CIMT measurements revealed statistically significant differences, with males being significantly at higher risk. A 10-year CVD risk assessment revealed higher risk among males and was statistically significant. It was found that a significant association between increased 10-year CVD risk and HbA1c, HDL, systolic BP, diastolic BP, and CIMT existed. Conclusions Comparison within gender among diabetic patients revealed that the cardiovascular risk factors were statistically higher among males as per 10-year risk assessment using the WHO/ISH chart.
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