含不消化糊精的枇杷膏加蔗糖抑制血糖的研究

H. Beppu, Y. Matsumoto, Haruo Watanabe, S. Sonoda, Tatsunori Nakano, T. Higashiguchi, Eiko Takeshige, Y. Shiino, N. Doi, H. Shimpo
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摘要

将含有89%不消化糊精、6%薏苡仁(Coix lacrima-jobi L. var. ma-yuen Stapf)和5%马尾(Equisetum arvense L.)的8 g粒状保健食品Kentoh-Rakucha(试验样品名称:CD-1)悬浮在200 mL水中,并给予受试者,受试者随后给予150 mL 71.2 g蔗糖溶液。20名健康志愿者在服用测试食物(CD-1)约6分钟后接受了150毫升的蔗糖溶液,并与20名在服用相同的蔗糖溶液之前接受安慰剂食物(不含难以消化的糊精)的志愿者进行了血糖水平检测。CD-1组和安慰剂组的血糖水平在加载蔗糖溶液后30分钟达到峰值。与安慰剂组相比,CD-1组的血糖水平和AUC得到有效抑制。然而,不消化糊精引起的血糖和胰岛素水平之间没有相关性。因此,该产品可有效抑制摄入富含淀粉和糖的膳食后血糖水平和葡萄糖AUC的快速升高。
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Study of Blood Glucose Suppression by Kentoh-Rakucha Containing Indigestible Dextrin after Loading with Sucrose Solution
An 8 g portion of the granular health food Kentoh-Rakucha (test sample name: CD-1), consisting of 89% indigestible dextrin, 6% Coix seed (Coix lacrima-jobi L. var. ma-yuen Stapf), and 5% horsetail (Equisetum arvense L.), which contains indigestible dextrin in the form of soluble dietary fiber, was suspended in 200 mL of water and administered to test subjects, who were then given 150 mL of a 71.2 g sucrose solution. The 20 healthy volunteers who received 150 mL of the sucrose solution about six minutes after administration of the test food (CD-1) were examined for blood glucose level in comparison with 20 matched volunteers who received a placebo food (not containing indigestible dextrin) before loading with the same sucrose solution. Blood glucose levels in the CD-1 group and the placebo group peaked at 30 minutes after loading with the sucrose solution. Blood glucose level and AUC were effectively suppressed in the CD-1 group in comparison with the placebo group. There was however no correlation between blood glucose and the insulin levels induced by the indigestible dextrin. The product was thus effective in the suppression of rapid increase in blood glucose level and glucose AUC after ingestion of a starchand sugar-rich meal.
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