{"title":"重症监护病房的念珠菌感染:如何治疗?","authors":"E. Kazak","doi":"10.5152/kd.2019.60","DOIUrl":null,"url":null,"abstract":"The number of fungal infections observed in hospitalized patients has been gradually increasing in recent years. Bloodstream infections due to Candida spp. constitute the majority of hospital-acquired fungal infections. Two-thirds of all candidemias occur in patients in the intensive care units. Early initiation of appropriate treatment decreases high mortality in these cases. On the other hand, difficulty in diagnosis, economic cost of drug treatments, development of resistance, and effect of unnecessary drug use on ecology are major obstacles to the initiation of treatment. The recommendations on which conditions, in which patients, and when and which antifungal therapy should be initiated are discussed in this review. Klimik Dergisi 2019; 32(Suppl. 2):154-62.","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Candida Infections in Intensive Care Unit: How to Treat?\",\"authors\":\"E. Kazak\",\"doi\":\"10.5152/kd.2019.60\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The number of fungal infections observed in hospitalized patients has been gradually increasing in recent years. Bloodstream infections due to Candida spp. constitute the majority of hospital-acquired fungal infections. Two-thirds of all candidemias occur in patients in the intensive care units. Early initiation of appropriate treatment decreases high mortality in these cases. On the other hand, difficulty in diagnosis, economic cost of drug treatments, development of resistance, and effect of unnecessary drug use on ecology are major obstacles to the initiation of treatment. The recommendations on which conditions, in which patients, and when and which antifungal therapy should be initiated are discussed in this review. Klimik Dergisi 2019; 32(Suppl. 2):154-62.\",\"PeriodicalId\":17826,\"journal\":{\"name\":\"Klimik Dergisi/Klimik Journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Klimik Dergisi/Klimik Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5152/kd.2019.60\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Klimik Dergisi/Klimik Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5152/kd.2019.60","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
近年来,住院患者真菌感染的数量逐渐增加。念珠菌引起的血液感染是医院获得性真菌感染的主要原因。三分之二的念珠菌发生在重症监护病房的患者中。及早开始适当治疗可降低这些病例的高死亡率。另一方面,诊断困难、药物治疗的经济成本、耐药性的发展以及不必要的药物使用对生态的影响是开始治疗的主要障碍。在这篇综述中讨论了哪些条件,哪些患者,何时以及哪种抗真菌治疗应该开始的建议。Klimik Dergisi 2019;32(5。2): 154 - 62。
Candida Infections in Intensive Care Unit: How to Treat?
The number of fungal infections observed in hospitalized patients has been gradually increasing in recent years. Bloodstream infections due to Candida spp. constitute the majority of hospital-acquired fungal infections. Two-thirds of all candidemias occur in patients in the intensive care units. Early initiation of appropriate treatment decreases high mortality in these cases. On the other hand, difficulty in diagnosis, economic cost of drug treatments, development of resistance, and effect of unnecessary drug use on ecology are major obstacles to the initiation of treatment. The recommendations on which conditions, in which patients, and when and which antifungal therapy should be initiated are discussed in this review. Klimik Dergisi 2019; 32(Suppl. 2):154-62.