适用于各类普查的贝叶斯时空生存分析,并应用于一项野生动物疾病研究

IF 1.5 3区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Environmetrics Pub Date : 2023-08-01 DOI:10.1002/env.2823
Kehui Yao, Jun Zhu, Daniel J. O'Brien, Daniel Walsh
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引用次数: 0

摘要

在本文中,我们考虑用时空协变量对任意删失的生存数据建模。我们证明,在片断恒定危险函数下,未删失或右删失受试者的可能性与多个条件独立泊松随机变量的可能性成正比。为了解决左删失或区间删失受试者的问题,我们建议估算确切的事件时间,并将其转换为未删失受试者,从而能够应用集成嵌套拉普拉斯近似法,利用估算数据更新模型参数。我们引入了一种迭代算法,该算法可交替计算左侧和间隔删失受试者的事件时间,并重新估计模型参数。我们通过模拟研究对所提出的方法进行了评估,并将其应用于分析密歇根州白尾鹿牛结核病野生动物疾病研究中的时空生存数据集。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Bayesian spatio-temporal survival analysis for all types of censoring with application to a wildlife disease study

In this article, we consider modeling arbitrarily censored survival data with spatio-temporal covariates. We demonstrate that under the piecewise constant hazard function, the likelihood for uncensored or right-censored subjects is proportional to the likelihood of multiple conditionally independent Poisson random variables. To address left- or interval-censored subjects, we propose to impute the exact event times and convert them into uncensored subjects, enabling the application of the integrated nested Laplace approximation to update model parameters using the imputed data. We introduce an iterative algorithm that alternates between imputing event times for left- and interval-censored subjects and re-estimating model parameters. The proposed method is assessed through a simulation study and applied to analyze a spatio-temporal survival dataset in a wildlife disease study investigating bovine tuberculosis in white-tailed deer in Michigan.

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来源期刊
Environmetrics
Environmetrics 环境科学-环境科学
CiteScore
2.90
自引率
17.60%
发文量
67
审稿时长
18-36 weeks
期刊介绍: Environmetrics, the official journal of The International Environmetrics Society (TIES), an Association of the International Statistical Institute, is devoted to the dissemination of high-quality quantitative research in the environmental sciences. The journal welcomes pertinent and innovative submissions from quantitative disciplines developing new statistical and mathematical techniques, methods, and theories that solve modern environmental problems. Articles must proffer substantive, new statistical or mathematical advances to answer important scientific questions in the environmental sciences, or must develop novel or enhanced statistical methodology with clear applications to environmental science. New methods should be illustrated with recent environmental data.
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