弥散性血管内凝血与SARS-COV-2感染相关:一个死后病例研究

Cláudio Gleidiston Lima Da Silva, M.S. dos Santos, Sávio Samuel Feitosa Machado, Rosa Gabryella Barreto Tiburi, Marina Catunda Pinheiro Jucá, Luana Lima Barros, Ana Flávia Moreira de Carvalho, Bruna Raynara Novais Lima, João Pedro de Souza Bezerra,, Modesto Leite Rolim Neto
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引用次数: 0

摘要

COVID-19的凝血功能障碍机制复杂。然而,已经假设内皮病变和血小板活化可能是重要因素,导致内皮细胞直接损伤和炎症反应不平衡,表现为静脉动脉或微血管血栓形成。本文报道一例8岁女性患者病毒性脓毒症并发弥散性血管内凝血的临床病例。
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Disseminated Intravascular Coagulation Associated With SARS-COV-2 Infection: A Post- Mortem Case Study
The mechanisms of coagulation disorder in COVID-19 are complex. However, it is already postulated that endotheliopathy and platelet activation may be important factors, causing direct damage to endothelial cells and the imbalance of inflammatory response, manifesting by venous arterial or microvascular thrombosis. The present study aims to describe a clinical case of an 8-year-old female patient with disseminated intravascular coagulation due to sepsis of viral etiology.
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