Nabeel Aslam, Hengyun Zhou, Elana K. Urbach, Matthew J. Turner, Ronald L. Walsworth, Mikhail D. Lukin, Hongkun Park
{"title":"用于生物医学应用的量子传感器","authors":"Nabeel Aslam, Hengyun Zhou, Elana K. Urbach, Matthew J. Turner, Ronald L. Walsworth, Mikhail D. Lukin, Hongkun Park","doi":"10.1038/s42254-023-00558-3","DOIUrl":null,"url":null,"abstract":"Quantum sensors are finding their way from laboratories to the real world, as witnessed by the increasing number of start-ups in this field. The atomic length scale of quantum sensors and their coherence properties enable unprecedented spatial resolution and sensitivity. Biomedical applications could benefit from these quantum technologies, but it is often difficult to evaluate the potential impact of the techniques. This Review sheds light on these questions, presenting the status of quantum sensing applications and discussing their path towards commercialization. The focus is on two promising quantum sensing platforms: optically pumped atomic magnetometers, and nitrogen–vacancy centres in diamond. The broad spectrum of biomedical applications is highlighted by four case studies ranging from brain imaging to single-cell spectroscopy. Quantum sensors enable new possibilities in biomedical applications due to their high sensitivity. In this Review, the status of quantum sensing is presented, and the path towards real-world applications on the molecular, cellular and organism scale is evaluated.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"5 3","pages":"157-169"},"PeriodicalIF":44.8000,"publicationDate":"2023-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896461/pdf/","citationCount":"28","resultStr":"{\"title\":\"Quantum sensors for biomedical applications\",\"authors\":\"Nabeel Aslam, Hengyun Zhou, Elana K. Urbach, Matthew J. Turner, Ronald L. Walsworth, Mikhail D. Lukin, Hongkun Park\",\"doi\":\"10.1038/s42254-023-00558-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Quantum sensors are finding their way from laboratories to the real world, as witnessed by the increasing number of start-ups in this field. The atomic length scale of quantum sensors and their coherence properties enable unprecedented spatial resolution and sensitivity. Biomedical applications could benefit from these quantum technologies, but it is often difficult to evaluate the potential impact of the techniques. This Review sheds light on these questions, presenting the status of quantum sensing applications and discussing their path towards commercialization. The focus is on two promising quantum sensing platforms: optically pumped atomic magnetometers, and nitrogen–vacancy centres in diamond. The broad spectrum of biomedical applications is highlighted by four case studies ranging from brain imaging to single-cell spectroscopy. Quantum sensors enable new possibilities in biomedical applications due to their high sensitivity. In this Review, the status of quantum sensing is presented, and the path towards real-world applications on the molecular, cellular and organism scale is evaluated.\",\"PeriodicalId\":19024,\"journal\":{\"name\":\"Nature Reviews Physics\",\"volume\":\"5 3\",\"pages\":\"157-169\"},\"PeriodicalIF\":44.8000,\"publicationDate\":\"2023-02-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896461/pdf/\",\"citationCount\":\"28\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature Reviews Physics\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://www.nature.com/articles/s42254-023-00558-3\",\"RegionNum\":1,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PHYSICS, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Physics","FirstCategoryId":"101","ListUrlMain":"https://www.nature.com/articles/s42254-023-00558-3","RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PHYSICS, APPLIED","Score":null,"Total":0}
Quantum sensors are finding their way from laboratories to the real world, as witnessed by the increasing number of start-ups in this field. The atomic length scale of quantum sensors and their coherence properties enable unprecedented spatial resolution and sensitivity. Biomedical applications could benefit from these quantum technologies, but it is often difficult to evaluate the potential impact of the techniques. This Review sheds light on these questions, presenting the status of quantum sensing applications and discussing their path towards commercialization. The focus is on two promising quantum sensing platforms: optically pumped atomic magnetometers, and nitrogen–vacancy centres in diamond. The broad spectrum of biomedical applications is highlighted by four case studies ranging from brain imaging to single-cell spectroscopy. Quantum sensors enable new possibilities in biomedical applications due to their high sensitivity. In this Review, the status of quantum sensing is presented, and the path towards real-world applications on the molecular, cellular and organism scale is evaluated.
期刊介绍:
Nature Reviews Physics is an online-only reviews journal, part of the Nature Reviews portfolio of journals. It publishes high-quality technical reference, review, and commentary articles in all areas of fundamental and applied physics. The journal offers a range of content types, including Reviews, Perspectives, Roadmaps, Technical Reviews, Expert Recommendations, Comments, Editorials, Research Highlights, Features, and News & Views, which cover significant advances in the field and topical issues. Nature Reviews Physics is published monthly from January 2019 and does not have external, academic editors. Instead, all editorial decisions are made by a dedicated team of full-time professional editors.