R. Najafipour, J. Ansari, Manijeh Jalilvand, S. Moghbelinejad
{"title":"卡兹温地区自然流产、死产和复发性流产夫妇的细胞遗传学评价:报道与回顾","authors":"R. Najafipour, J. Ansari, Manijeh Jalilvand, S. Moghbelinejad","doi":"10.17795/BHS-35388","DOIUrl":null,"url":null,"abstract":"Background: Chromosomal abnormality plays an important role in different types of miscarriages. \nObjectives: The present study was designed to investigation chromosomal anomalies in three groups of couples with recurrent \nabortion (RA), spontaneous abortion (SA) and still birth (SB). \nPatientsandMethods: In this retrospective study, the frequency of chromosomal aberrations was investigatedamong 260 couples \nwith miscarriage, which had referred to the cytogenetic section of a reference laboratory in Buali hospilal, Qazvin, Iran from 2009 \nto 2014. Metaphase spreads were analyzed using G-banding. \nResults: In this study, 7.6% of couples had chromosomal aberrations including, balanced reciprocal translocations, robertsonian \ntranslocations, inversions and sex chromosome aneuploidy. Frequency of balanced translocations was higher, specifically in couples \nwith SA. \nConclusions: In this investigation we showed that chromosomal abnormalities could be one of the important causes of miscarriages. \nCytogenetic evaluation of couples, which experienced different types of miscarriage, may prevent unnecessary treatments. \nKeywords: Recurrent Abortion, Spontaneous Abortion, Still Birth, Chromosome Abnormality","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":"65 1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Cytogenetic Evaluation of Couples With Spontaneous Abortion, Still Birth and Recurrent Miscarriage in Qazvin: Report and Review\",\"authors\":\"R. Najafipour, J. Ansari, Manijeh Jalilvand, S. Moghbelinejad\",\"doi\":\"10.17795/BHS-35388\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Chromosomal abnormality plays an important role in different types of miscarriages. \\nObjectives: The present study was designed to investigation chromosomal anomalies in three groups of couples with recurrent \\nabortion (RA), spontaneous abortion (SA) and still birth (SB). \\nPatientsandMethods: In this retrospective study, the frequency of chromosomal aberrations was investigatedamong 260 couples \\nwith miscarriage, which had referred to the cytogenetic section of a reference laboratory in Buali hospilal, Qazvin, Iran from 2009 \\nto 2014. Metaphase spreads were analyzed using G-banding. \\nResults: In this study, 7.6% of couples had chromosomal aberrations including, balanced reciprocal translocations, robertsonian \\ntranslocations, inversions and sex chromosome aneuploidy. Frequency of balanced translocations was higher, specifically in couples \\nwith SA. \\nConclusions: In this investigation we showed that chromosomal abnormalities could be one of the important causes of miscarriages. \\nCytogenetic evaluation of couples, which experienced different types of miscarriage, may prevent unnecessary treatments. \\nKeywords: Recurrent Abortion, Spontaneous Abortion, Still Birth, Chromosome Abnormality\",\"PeriodicalId\":8849,\"journal\":{\"name\":\"Biotechnology and Health Sciences\",\"volume\":\"65 1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-03-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biotechnology and Health Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17795/BHS-35388\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biotechnology and Health Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17795/BHS-35388","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Cytogenetic Evaluation of Couples With Spontaneous Abortion, Still Birth and Recurrent Miscarriage in Qazvin: Report and Review
Background: Chromosomal abnormality plays an important role in different types of miscarriages.
Objectives: The present study was designed to investigation chromosomal anomalies in three groups of couples with recurrent
abortion (RA), spontaneous abortion (SA) and still birth (SB).
PatientsandMethods: In this retrospective study, the frequency of chromosomal aberrations was investigatedamong 260 couples
with miscarriage, which had referred to the cytogenetic section of a reference laboratory in Buali hospilal, Qazvin, Iran from 2009
to 2014. Metaphase spreads were analyzed using G-banding.
Results: In this study, 7.6% of couples had chromosomal aberrations including, balanced reciprocal translocations, robertsonian
translocations, inversions and sex chromosome aneuploidy. Frequency of balanced translocations was higher, specifically in couples
with SA.
Conclusions: In this investigation we showed that chromosomal abnormalities could be one of the important causes of miscarriages.
Cytogenetic evaluation of couples, which experienced different types of miscarriage, may prevent unnecessary treatments.
Keywords: Recurrent Abortion, Spontaneous Abortion, Still Birth, Chromosome Abnormality
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