microRNA及miRNA-CNVs先天性心脏缺陷的研究进展

Yuan Tian, Yanxiao Liang, H. Pang
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引用次数: 0

摘要

先天性心脏病(CHD)是中国最常见的出生缺陷。然而,大多数冠心病的病因尚不清楚。近年来,随着分子诊断技术的发展,一些研究者开始关注在冠心病患儿中检测到的cnv中的microRNA。然而,CNVs中的microRNA (miRNA-CNVs)作为冠心病的遗传机制尚不确定。本文就microRNA、CNVs、miRNA-CNVs与冠心病关系的研究进展进行综述。
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Research progress on microRNA and miRNA-CNVs congenital heart defects
Congenital heart defects(CHD) are the most common birth defects in China. However, the etiology of most CHD remains unclear. In recent years, with the development of molecular diagnostic techniques, some researchers began to pay attention to microRNA in CNVs detected in CHD children. However, microRNA in CNVs(miRNA-CNVs) as a genetic mechanism in CHD is not known with certainty. So the research progress of the relationship between microRNA, CNVs, miRNA-CNVs and CHD were summarized in this paper.
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